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    CHN1 chimerin 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 478805, updated on 17-Aug-2024

    Summary

    Official Symbol
    CHN1provided by VGNC
    Official Full Name
    chimerin 1provided by VGNC
    Primary source
    VGNC:VGNC:56135
    See related
    Ensembl:ENSCAFG00845017147
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See CHN1 in Genome Data Viewer
    Location:
    chromosome: 36
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 36 NC_051840.1 (18922240..19128093, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 36 NC_006618.4 (18794209..18999749, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 36 NC_049257.1 (19107993..19313290, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 36 NC_049296.1 (18998481..19204056, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 36 NC_049777.1 (18997206..19202881, complement)

    Chromosome 36 - NC_051840.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867834 Neighboring gene uncharacterized LOC111094229 Neighboring gene WAS/WASL interacting protein family member 1 Neighboring gene cholinergic receptor nicotinic alpha 1 subunit Neighboring gene uncharacterized LOC119867835 Neighboring gene uncharacterized LOC102155817 Neighboring gene guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like Neighboring gene activating transcription factor 2 Neighboring gene ATP synthase membrane subunit c locus 3

    Genomic regions, transcripts, and products

    General protein information

    Preferred Names
    N-chimaerin
    Names
    chimerin (chimaerin) 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051840.1 Reference ROS_Cfam_1.0

      Range
      18922240..19128093 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038447117.1XP_038303045.1  N-chimaerin isoform X6

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cl00040
      Location:202233
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:227394
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    2. XM_038447114.1XP_038303042.1  N-chimaerin isoform X3

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:259452
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20806
      Location:202250
      C1_CHN; protein kinase C conserved region 1 (C1 domain) found in the chimaerin family
    3. XM_038447116.1XP_038303044.1  N-chimaerin isoform X5

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cl00040
      Location:220259
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:253420
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    4. XM_038447112.1XP_038303040.1  N-chimaerin isoform X1

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:285478
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:220276
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    5. XM_038447119.1XP_038303047.1  N-chimaerin isoform X8

      UniProtKB/TrEMBL
      A0A8C0NTF6, A0A8C0STS7, A0A8I3P278, A0A8I3S2J9
      Related
      ENSCAFP00845024008.1, ENSCAFT00845030601.1
      Conserved Domains (3) summary
      cd10352
      Location:42128
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:266459
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:201257
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    6. XM_038447113.1XP_038303041.1  N-chimaerin isoform X2

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:57143
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:281474
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:216272
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    7. XM_038447115.1XP_038303043.1  N-chimaerin isoform X4

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd04372
      Location:232425
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:167223
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
      cl15255
      Location:1694
      SH2; Src homology 2 (SH2) domain
    8. XM_038447118.1XP_038303046.1  N-chimaerin isoform X7

      Conserved Domains (3) summary
      cd04372
      Location:194387
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:129185
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
      cl15255
      Location:1656
      SH2; Src homology 2 (SH2) domain
    9. XM_038447120.1XP_038303048.1  N-chimaerin isoform X9

      UniProtKB/TrEMBL
      A0A8C0NTK4, A0A8I3NXK7
      Related
      ENSCAFP00845024147.1, ENSCAFT00845030798.1
      Conserved Domains (2) summary
      cd04372
      Location:86279
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cl00040
      Location:2280
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
    10. XM_038447121.1XP_038303049.1  N-chimaerin isoform X10

      UniProtKB/TrEMBL
      A0A8C0JYI0, A0A8C0JZR2
      Conserved Domains (2) summary
      cl00040
      Location:76115
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:109276
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049296.1 Alternate UMICH_Zoey_3.1

      Range
      18998481..19204056 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038521196.1XP_038377124.1  N-chimaerin isoform X6

      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cl00040
      Location:202233
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:227394
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    2. XM_038521193.1XP_038377121.1  N-chimaerin isoform X3

      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:259452
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20806
      Location:202250
      C1_CHN; protein kinase C conserved region 1 (C1 domain) found in the chimaerin family
    3. XM_038521195.1XP_038377123.1  N-chimaerin isoform X5

      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cl00040
      Location:220259
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:253420
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    4. XM_038521191.1XP_038377119.1  N-chimaerin isoform X1

      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:285478
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:220276
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    5. XM_038521198.1XP_038377126.1  N-chimaerin isoform X8

      Conserved Domains (3) summary
      cd10352
      Location:42128
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:266459
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:201257
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    6. XM_038521192.1XP_038377120.1  N-chimaerin isoform X2

      Conserved Domains (3) summary
      cd10352
      Location:57143
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:281474
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:216272
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    7. XM_038521194.1XP_038377122.1  N-chimaerin isoform X4

      Conserved Domains (3) summary
      cd04372
      Location:232425
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:167223
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
      cl15255
      Location:1694
      SH2; Src homology 2 (SH2) domain
    8. XM_038521197.1XP_038377125.1  N-chimaerin isoform X7

      Conserved Domains (3) summary
      cd04372
      Location:194387
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:129185
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
      cl15255
      Location:1656
      SH2; Src homology 2 (SH2) domain
    9. XM_038521199.1XP_038377127.1  N-chimaerin isoform X9

      Conserved Domains (2) summary
      cd04372
      Location:86279
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cl00040
      Location:2280
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
    10. XM_038521200.1XP_038377128.1  N-chimaerin isoform X10

      Conserved Domains (2) summary
      cl00040
      Location:76115
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:109276
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049777.1 Alternate UNSW_CanFamBas_1.0

      Range
      18997206..19202881 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038649315.1XP_038505243.1  N-chimaerin isoform X6

      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cl00040
      Location:202233
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:227394
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    2. XM_038649312.1XP_038505240.1  N-chimaerin isoform X3

      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:259452
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20806
      Location:202250
      C1_CHN; protein kinase C conserved region 1 (C1 domain) found in the chimaerin family
    3. XM_038649314.1XP_038505242.1  N-chimaerin isoform X5

      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cl00040
      Location:220259
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:253420
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    4. XM_038649310.1XP_038505238.1  N-chimaerin isoform X1

      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:285478
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:220276
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    5. XM_038649317.1XP_038505245.1  N-chimaerin isoform X8

      Conserved Domains (3) summary
      cd10352
      Location:42128
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:266459
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:201257
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    6. XM_038649311.1XP_038505239.1  N-chimaerin isoform X2

      Conserved Domains (3) summary
      cd10352
      Location:57143
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:281474
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:216272
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    7. XM_038649313.1XP_038505241.1  N-chimaerin isoform X4

      Conserved Domains (3) summary
      cd04372
      Location:232425
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:167223
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
      cl15255
      Location:1694
      SH2; Src homology 2 (SH2) domain
    8. XM_038649316.1XP_038505244.1  N-chimaerin isoform X7

      Conserved Domains (3) summary
      cd04372
      Location:194387
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:129185
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
      cl15255
      Location:1656
      SH2; Src homology 2 (SH2) domain
    9. XM_038649318.1XP_038505246.1  N-chimaerin isoform X9

      Conserved Domains (2) summary
      cd04372
      Location:86279
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cl00040
      Location:2280
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
    10. XM_038649319.1XP_038505247.1  N-chimaerin isoform X10

      Conserved Domains (2) summary
      cl00040
      Location:76115
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:109276
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049257.1 Alternate UU_Cfam_GSD_1.0

      Range
      19107993..19313290 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038584899.1XP_038440827.1  N-chimaerin isoform X6

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cl00040
      Location:202233
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:227394
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    2. XM_038584896.1XP_038440824.1  N-chimaerin isoform X3

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:259452
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20806
      Location:202250
      C1_CHN; protein kinase C conserved region 1 (C1 domain) found in the chimaerin family
    3. XM_038584898.1XP_038440826.1  N-chimaerin isoform X5

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cl00040
      Location:220259
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:253420
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    4. XM_038584894.1XP_038440822.1  N-chimaerin isoform X1

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:285478
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:220276
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    5. XM_038584902.1XP_038440830.1  N-chimaerin isoform X8

      UniProtKB/TrEMBL
      A0A8C0NTF6, A0A8C0STS7, A0A8I3P278, A0A8I3S2J9
      Conserved Domains (3) summary
      cd10352
      Location:42128
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:266459
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:201257
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    6. XM_038584895.1XP_038440823.1  N-chimaerin isoform X2

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:57143
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:281474
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:216272
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    7. XM_038584897.1XP_038440825.1  N-chimaerin isoform X4

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd04372
      Location:232425
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:167223
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
      cl15255
      Location:1694
      SH2; Src homology 2 (SH2) domain
    8. XM_038584900.1XP_038440828.1  N-chimaerin isoform X7

      Conserved Domains (3) summary
      cd04372
      Location:194387
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:129185
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
      cl15255
      Location:1656
      SH2; Src homology 2 (SH2) domain
    9. XM_038584903.1XP_038440831.1  N-chimaerin isoform X9

      UniProtKB/TrEMBL
      A0A8C0NTK4, A0A8I3NXK7
      Conserved Domains (2) summary
      cd04372
      Location:86279
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cl00040
      Location:2280
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
    10. XM_038584904.1XP_038440832.1  N-chimaerin isoform X10

      UniProtKB/TrEMBL
      A0A8C0JYI0, A0A8C0JZR2
      Conserved Domains (2) summary
      cl00040
      Location:76115
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:109276
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006618.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      18794209..18999749 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038463494.1XP_038319422.1  N-chimaerin isoform X6

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cl00040
      Location:202233
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:227394
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    2. XM_038463491.1XP_038319419.1  N-chimaerin isoform X3

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:259452
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20806
      Location:202250
      C1_CHN; protein kinase C conserved region 1 (C1 domain) found in the chimaerin family
    3. XM_038463493.1XP_038319421.1  N-chimaerin isoform X5

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cl00040
      Location:220259
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:253420
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    4. XM_022414787.1XP_022270495.1  N-chimaerin isoform X1

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:61147
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:285478
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:220276
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    5. XM_038463495.1XP_038319423.1  N-chimaerin isoform X8

      UniProtKB/TrEMBL
      A0A8C0NTF6, A0A8C0STS7, A0A8I3P278, A0A8I3S2J9
      Conserved Domains (3) summary
      cd10352
      Location:42128
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:266459
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:201257
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    6. XM_022414785.2XP_022270493.1  N-chimaerin isoform X2

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd10352
      Location:57143
      SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
      cd04372
      Location:281474
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:216272
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
    7. XM_038463492.1XP_038319420.1  N-chimaerin isoform X4

      UniProtKB/TrEMBL
      A0A8C0STS7, A0A8I3P278
      Conserved Domains (3) summary
      cd04372
      Location:232425
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:167223
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
      cl15255
      Location:1694
      SH2; Src homology 2 (SH2) domain
    8. XM_014110693.1XP_013966168.1  N-chimaerin isoform X7

      Conserved Domains (3) summary
      cd04372
      Location:194387
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cd20856
      Location:129185
      C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins
      cl15255
      Location:1656
      SH2; Src homology 2 (SH2) domain
    9. XM_845334.4XP_850427.2  N-chimaerin isoform X9

      UniProtKB/TrEMBL
      A0A8C0NTK4, A0A8I3NXK7
      Conserved Domains (2) summary
      cd04372
      Location:86279
      RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
      cl00040
      Location:2280
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
    10. XM_005640333.4XP_005640390.1  N-chimaerin isoform X10

      UniProtKB/TrEMBL
      A0A8C0JYI0, A0A8C0JZR2
      Conserved Domains (2) summary
      cl00040
      Location:76115
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
      cl02570
      Location:109276
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...