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    HPGDS hematopoietic prostaglandin D synthase [ Canis lupus familiaris (dog) ]

    Gene ID: 478481, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HPGDSprovided by VGNC
    Official Full Name
    hematopoietic prostaglandin D synthaseprovided by VGNC
    Primary source
    VGNC:VGNC:54312
    See related
    Ensembl:ENSCAFG00845020740
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    H-PGDS
    Orthologs
    human mouse all
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    Genomic context

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    See HPGDS in Genome Data Viewer
    Location:
    chromosome: 32
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 32 NC_051836.1 (17315689..17375451, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 32 NC_006614.4 (24752940..24777413)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 32 NC_049253.1 (22730052..22754426)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 32 NC_049292.1 (17323037..17347505, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 32 NC_049773.1 (17137331..17161789, complement)

    Chromosome 32 - NC_051836.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106558121 Neighboring gene uncharacterized LOC106558143 Neighboring gene SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 Neighboring gene PDZ and LIM domain 5 Neighboring gene ubiquitin-conjugating enzyme E2 variant 1-like Neighboring gene uncharacterized LOC111093604 Neighboring gene bone morphogenetic protein receptor type 1B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutathione transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hematopoietic prostaglandin D synthase
    NP_001186973.1
    XP_038299712.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001200044.3 → NP_001186973.1  hematopoietic prostaglandin D synthase

      See identical proteins and their annotated locations for NP_001186973.1

      Status: VALIDATED

      Source sequence(s)
      JAAUVH010000366
      UniProtKB/TrEMBL
      A0A8C0JR43, A0A8C0PBV7, E5RQH2
      Related
      ENSCAFP00845028615.1, ENSCAFT00845036567.1
      Conserved Domains (2) summary
      cd10295
      Location:82 → 181
      GST_C_Sigma; C-terminal, alpha helical domain of Class Sigma Glutathione S-transferases
      cd03039
      Location:4 → 73
      GST_N_Sigma_like; GST_N family, Class Sigma_like; composed of GSTs belonging to class Sigma and similar proteins, including GSTs from class Mu, Pi and Alpha. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of ...

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051836.1 Reference ROS_Cfam_1.0

      Range
      17315689..17375451 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038443784.1 → XP_038299712.1  hematopoietic prostaglandin D synthase isoform X1

      Conserved Domains (2) summary
      cd10295
      Location:82 → 172
      GST_C_Sigma; C-terminal, alpha helical domain of Class Sigma Glutathione S-transferases
      cd03039
      Location:4 → 73
      GST_N_Sigma_like; GST_N family, Class Sigma_like; composed of GSTs belonging to class Sigma and similar proteins, including GSTs from class Mu, Pi and Alpha. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of ...

    RNA

    1. XR_005305579.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049292.1 Alternate UMICH_Zoey_3.1

      Range
      17323037..17347505 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049773.1 Alternate UNSW_CanFamBas_1.0

      Range
      17137331..17161789 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049253.1 Alternate UU_Cfam_GSD_1.0

      Range
      22730052..22754426
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006614.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      24752940..24777413
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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