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    MAPK10 mitogen-activated protein kinase 10 [ Canis lupus familiaris (dog) ]

    Gene ID: 478464, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MAPK10provided by VGNC
    Official Full Name
    mitogen-activated protein kinase 10provided by VGNC
    Primary source
    VGNC:VGNC:42992
    See related
    Ensembl:ENSCAFG00845023201
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See MAPK10 in Genome Data Viewer
    Location:
    chromosome: 32
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 32 NC_051836.1 (9607730..9912898, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 32 NC_006614.4 (32059481..32299296)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 32 NC_049253.1 (30098318..30403778)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 32 NC_049292.1 (9698411..10025887, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 32 NC_049773.1 (9545360..9851058, complement)

    Chromosome 32 - NC_051836.1Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 24 Neighboring gene developmentally-regulated GTP-binding protein 1-like Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC102156639 Neighboring gene U6 spliceosomal RNA Neighboring gene 60S ribosomal protein L17 Neighboring gene cyclin-J-like protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables JUN kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in JNK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase 10
    XP_005639202.1
    XP_005639203.1
    XP_005639205.1
    XP_013965479.1
    XP_022269113.1
    XP_022269115.1
    XP_022269116.1
    XP_038299970.1
    XP_038299971.1
    XP_038299972.1
    XP_038299973.1
    XP_038299974.1
    XP_038299975.1
    XP_038299976.1
    XP_038299978.1
    XP_038299979.1
    XP_038318055.1
    XP_038374367.1
    XP_038374368.1
    XP_038374369.1
    XP_038374370.1
    XP_038374371.1
    XP_038374372.1
    XP_038374373.1
    XP_038374374.1
    XP_038374376.1
    XP_038438149.1
    XP_038438150.1
    XP_038438151.1
    XP_038438152.1
    XP_038438153.1
    XP_038438154.1
    XP_038438155.1
    XP_038438156.1
    XP_038438157.1
    XP_038502302.1
    XP_038502303.1
    XP_038502304.1
    XP_038502305.1
    XP_038502306.1
    XP_038502307.1
    XP_038502308.1
    XP_038502309.1
    XP_038502310.1
    XP_859895.2
    XP_859929.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051836.1 Reference ROS_Cfam_1.0

      Range
      9607730..9912898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038444046.1 → XP_038299974.1  mitogen-activated protein kinase 10 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0MYT2
      Related
      ENSCAFP00845032995.1, ENSCAFT00845042067.1
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    2. XM_038444042.1 → XP_038299970.1  mitogen-activated protein kinase 10 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0TWL4
      Related
      ENSCAFP00845033146.1, ENSCAFT00845042282.1
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    3. XM_038444051.1 → XP_038299979.1  mitogen-activated protein kinase 10 isoform X4

      UniProtKB/TrEMBL
      A0A8C0KAD6, A0A8C0MW11, A0A8I3S3W6, A0A8P0T082
      Related
      ENSCAFP00845032909.1, ENSCAFT00845041959.1
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    4. XM_038444044.1 → XP_038299972.1  mitogen-activated protein kinase 10 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0TWL4
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    5. XM_038444048.1 → XP_038299976.1  mitogen-activated protein kinase 10 isoform X3

      UniProtKB/TrEMBL
      A0A8P0SEG5
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    6. XM_038444050.1 → XP_038299978.1  mitogen-activated protein kinase 10 isoform X3

      UniProtKB/TrEMBL
      A0A8P0SEG5
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    7. XM_038444047.1 → XP_038299975.1  mitogen-activated protein kinase 10 isoform X3

      UniProtKB/TrEMBL
      A0A8P0SEG5
      Related
      ENSCAFP00845032502.1, ENSCAFT00845041449.1
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    8. XM_038444045.1 → XP_038299973.1  mitogen-activated protein kinase 10 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0TWL4
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    9. XM_038444043.1 → XP_038299971.1  mitogen-activated protein kinase 10 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0TWL4
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049292.1 Alternate UMICH_Zoey_3.1

      Range
      9698411..10025887 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038518443.1 → XP_038374371.1  mitogen-activated protein kinase 10 isoform X2

      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    2. XM_038518439.1 → XP_038374367.1  mitogen-activated protein kinase 10 isoform X1

      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    3. XM_038518448.1 → XP_038374376.1  mitogen-activated protein kinase 10 isoform X4

      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    4. XM_038518441.1 → XP_038374369.1  mitogen-activated protein kinase 10 isoform X1

      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    5. XM_038518445.1 → XP_038374373.1  mitogen-activated protein kinase 10 isoform X3

      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    6. XM_038518446.1 → XP_038374374.1  mitogen-activated protein kinase 10 isoform X3

      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    7. XM_038518444.1 → XP_038374372.1  mitogen-activated protein kinase 10 isoform X3

      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    8. XM_038518442.1 → XP_038374370.1  mitogen-activated protein kinase 10 isoform X1

      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    9. XM_038518440.1 → XP_038374368.1  mitogen-activated protein kinase 10 isoform X1

      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049773.1 Alternate UNSW_CanFamBas_1.0

      Range
      9545360..9851058 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038646378.1 → XP_038502306.1  mitogen-activated protein kinase 10 isoform X2

      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    2. XM_038646374.1 → XP_038502302.1  mitogen-activated protein kinase 10 isoform X1

      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    3. XM_038646382.1 → XP_038502310.1  mitogen-activated protein kinase 10 isoform X4

      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    4. XM_038646376.1 → XP_038502304.1  mitogen-activated protein kinase 10 isoform X1

      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    5. XM_038646380.1 → XP_038502308.1  mitogen-activated protein kinase 10 isoform X3

      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    6. XM_038646381.1 → XP_038502309.1  mitogen-activated protein kinase 10 isoform X3

      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    7. XM_038646379.1 → XP_038502307.1  mitogen-activated protein kinase 10 isoform X3

      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    8. XM_038646377.1 → XP_038502305.1  mitogen-activated protein kinase 10 isoform X1

      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    9. XM_038646375.1 → XP_038502303.1  mitogen-activated protein kinase 10 isoform X1

      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049253.1 Alternate UU_Cfam_GSD_1.0

      Range
      30098318..30403778
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038582223.1 → XP_038438151.1  mitogen-activated protein kinase 10 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0TWL4
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    2. XM_038582225.1 → XP_038438153.1  mitogen-activated protein kinase 10 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0MYT2
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    3. XM_038582221.1 → XP_038438149.1  mitogen-activated protein kinase 10 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0TWL4
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    4. XM_038582229.1 → XP_038438157.1  mitogen-activated protein kinase 10 isoform X4

      UniProtKB/TrEMBL
      A0A8C0KAD6, A0A8C0MW11, A0A8I3S3W6, A0A8P0T082
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    5. XM_038582226.1 → XP_038438154.1  mitogen-activated protein kinase 10 isoform X3

      UniProtKB/TrEMBL
      A0A8P0SEG5
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    6. XM_038582228.1 → XP_038438156.1  mitogen-activated protein kinase 10 isoform X3

      UniProtKB/TrEMBL
      A0A8P0SEG5
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    7. XM_038582227.1 → XP_038438155.1  mitogen-activated protein kinase 10 isoform X3

      UniProtKB/TrEMBL
      A0A8P0SEG5
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    8. XM_038582224.1 → XP_038438152.1  mitogen-activated protein kinase 10 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0TWL4
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    9. XM_038582222.1 → XP_038438150.1  mitogen-activated protein kinase 10 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0TWL4
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006614.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      32059481..32299296
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022413405.2 → XP_022269113.1  mitogen-activated protein kinase 10 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0TWL4
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    2. XM_854836.6 → XP_859929.1  mitogen-activated protein kinase 10 isoform X2

      See identical proteins and their annotated locations for XP_859929.1

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0MYT2
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    3. XM_854802.6 → XP_859895.2  mitogen-activated protein kinase 10 isoform X1

      See identical proteins and their annotated locations for XP_859895.2

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0TWL4
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    4. XM_005639148.4 → XP_005639205.1  mitogen-activated protein kinase 10 isoform X4

      See identical proteins and their annotated locations for XP_005639205.1

      UniProtKB/TrEMBL
      A0A8C0KAD6, A0A8C0MW11, A0A8I3S3W6, A0A8P0T082
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    5. XM_022413407.1 → XP_022269115.1  mitogen-activated protein kinase 10 isoform X3

      UniProtKB/TrEMBL
      A0A8P0SEG5
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    6. XM_022413408.2 → XP_022269116.1  mitogen-activated protein kinase 10 isoform X3

      UniProtKB/TrEMBL
      A0A8P0SEG5
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    7. XM_005639146.3 → XP_005639203.1  mitogen-activated protein kinase 10 isoform X3

      See identical proteins and their annotated locations for XP_005639203.1

      UniProtKB/TrEMBL
      A0A8P0SEG5
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    8. XM_014110004.2 → XP_013965479.1  mitogen-activated protein kinase 10 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0TWL4
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    9. XM_005639145.4 → XP_005639202.1  mitogen-activated protein kinase 10 isoform X1

      See identical proteins and their annotated locations for XP_005639202.1

      UniProtKB/TrEMBL
      A0A8C0KAF3, A0A8C0TWL4
      Conserved Domains (1) summary
      cd07850
      Location:63 → 398
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    10. XM_038462127.1 → XP_038318055.1  mitogen-activated protein kinase 10 isoform X3

      UniProtKB/TrEMBL
      A0A8P0SEG5
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase
    Nucleotide Protein
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