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    KDM1A lysine demethylase 1A [ Canis lupus familiaris (dog) ]

    Gene ID: 478193, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KDM1Aprovided by VGNC
    Official Full Name
    lysine demethylase 1Aprovided by VGNC
    Primary source
    VGNC:VGNC:42318
    See related
    Ensembl:ENSCAFG00845000177
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    AOF2; KDM1
    Orthologs
    human mouse all
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    Genomic context

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    See KDM1A in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (76872072..76934039, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (72818576..72880479, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (75705895..75767600, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (73694139..73755941, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (74702184..74764063, complement)

    Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111093602 Neighboring gene 5-hydroxytryptamine receptor 1D Neighboring gene proline-rich protein 2-like Neighboring gene leucine zipper protein 1 Neighboring gene testis expressed 46 Neighboring gene lactamase beta like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lysine-specific histone demethylase 1A
    Names
    amine oxidase (flavin containing) domain 2
    lysine (K)-specific demethylase 1
    XP_005617878.1
    XP_038326718.1
    XP_038326719.1
    XP_038326720.1
    XP_038387581.1
    XP_038387582.1
    XP_038387583.1
    XP_038451811.1
    XP_038451812.1
    XP_038451813.1
    XP_038515890.1
    XP_038515891.1
    XP_038515892.1
    XP_535366.2
    XP_866610.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051806.1 Reference ROS_Cfam_1.0

      Range
      76872072..76934039 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038659964.1 → XP_038515892.1  lysine-specific histone demethylase 1A isoform X3

      UniProtKB/TrEMBL
      A0A8C0L0B5
      Conserved Domains (2) summary
      PLN02328
      Location:184 → 826
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    2. XM_038659963.1 → XP_038515891.1  lysine-specific histone demethylase 1A isoform X2

      UniProtKB/TrEMBL
      A0A8C0PWR1, A0A8I3MA21
      Related
      ENSCAFP00845000200.1, ENSCAFT00845000287.1
      Conserved Domains (2) summary
      PLN02328
      Location:204 → 846
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    3. XM_038659962.1 → XP_038515890.1  lysine-specific histone demethylase 1A isoform X1

      UniProtKB/TrEMBL
      A0A8C0M261, A0A8I3RNY9
      Related
      ENSCAFP00845000198.1, ENSCAFT00845000283.1
      Conserved Domains (2) summary
      PLN02328
      Location:204 → 850
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049262.1 Alternate UMICH_Zoey_3.1

      Range
      73694139..73755941 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038470792.1 → XP_038326720.1  lysine-specific histone demethylase 1A isoform X3

      Conserved Domains (2) summary
      PLN02328
      Location:184 → 826
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    2. XM_038470791.1 → XP_038326719.1  lysine-specific histone demethylase 1A isoform X2

      Conserved Domains (2) summary
      PLN02328
      Location:204 → 846
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    3. XM_038470790.1 → XP_038326718.1  lysine-specific histone demethylase 1A isoform X1

      Conserved Domains (2) summary
      PLN02328
      Location:204 → 850
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

      Range
      74702184..74764063 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038595885.1 → XP_038451813.1  lysine-specific histone demethylase 1A isoform X3

      Conserved Domains (2) summary
      PLN02328
      Location:184 → 826
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    2. XM_038595884.1 → XP_038451812.1  lysine-specific histone demethylase 1A isoform X2

      Conserved Domains (2) summary
      PLN02328
      Location:204 → 846
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    3. XM_038595883.1 → XP_038451811.1  lysine-specific histone demethylase 1A isoform X1

      Conserved Domains (2) summary
      PLN02328
      Location:204 → 850
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

      Range
      75705895..75767600 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038531655.1 → XP_038387583.1  lysine-specific histone demethylase 1A isoform X3

      UniProtKB/TrEMBL
      A0A8C0L0B5
      Conserved Domains (2) summary
      PLN02328
      Location:184 → 826
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    2. XM_038531654.1 → XP_038387582.1  lysine-specific histone demethylase 1A isoform X2

      UniProtKB/TrEMBL
      A0A8C0PWR1, A0A8I3MA21
      Conserved Domains (2) summary
      PLN02328
      Location:204 → 846
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    3. XM_038531653.1 → XP_038387581.1  lysine-specific histone demethylase 1A isoform X1

      UniProtKB/TrEMBL
      A0A8C0M261, A0A8I3RNY9
      Conserved Domains (2) summary
      PLN02328
      Location:204 → 850
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      72818576..72880479 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_861517.5 → XP_866610.1  lysine-specific histone demethylase 1A isoform X3

      UniProtKB/TrEMBL
      A0A8C0L0B5
      Conserved Domains (2) summary
      PLN02328
      Location:184 → 826
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    2. XM_005617821.3 → XP_005617878.1  lysine-specific histone demethylase 1A isoform X2

      UniProtKB/TrEMBL
      A0A8C0PWR1, A0A8I3MA21
      Conserved Domains (2) summary
      PLN02328
      Location:204 → 846
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional

    3. XM_535366.7 → XP_535366.2  lysine-specific histone demethylase 1A isoform X1

      UniProtKB/TrEMBL
      A0A8C0M261, A0A8I3RNY9
      Conserved Domains (2) summary
      PLN02328
      Location:204 → 850
      PLN02328; lysine-specific histone demethylase 1 homolog
      PHA03378
      Location:39 → 99
      PHA03378; EBNA-3B; Provisional
    Nucleotide Protein
    Heading Accession and Version

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