PEBP1 phosphatidylethanolamine binding protein 1 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: PEBP1provided by VGNC
Official Full Name: phosphatidylethanolamine binding protein 1provided by VGNC
Primary source: VGNC:VGNC:111630
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: PBP
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 26

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	26	NC_051830.1 (14784007..14788255)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	26	NC_006608.4 (14515188..14519426)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	26	NC_049247.1 (14856217..14860448)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	26	NC_049286.1 (14748852..14753083)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	26	NC_049767.1 (14821104..14825345)

Chromosome 26 - NC_051830.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

RKIP-overexpressing cells generate considerably more contractile traction force than do control cells. In contrast, RNA interference-based silencing of RKIP expression results in decreased cell-substratum adhesion.
Title: Raf kinase inhibitor protein positively regulates cell-substratum adhesion while negatively regulating cell-cell adhesion.

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General gene information

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Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in negative regulation of MAPK cascade	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: phosphatidylethanolamine-binding protein 1

Names: HCNPpp; PEBP-1; RKIP; Raf kinase inhibitor protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001048092.1 → NP_001041557.1 phosphatidylethanolamine-binding protein 1

See identical proteins and their annotated locations for NP_001041557.1

Status: PROVISIONAL

Source sequence(s)

DQ130016

UniProtKB/Swiss-Prot

Q3YIX4

UniProtKB/TrEMBL

A0A8C0L1H2, A0A8C0SUU0

Conserved Domains (1) summary

cd00866
Location:25 → 171

PEBP_euk; PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in eukaryotes