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    SFTPC surfactant protein C [ Canis lupus familiaris (dog) ]

    Gene ID: 477385, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SFTPCprovided by VGNC
    Official Full Name
    surfactant protein Cprovided by VGNC
    Primary source
    VGNC:VGNC:54994
    See related
    Ensembl:ENSCAFG00845025534
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    SP-C; SFTP2
    Orthologs
    human mouse all
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    Genomic context

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    See SFTPC in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (35299616..35302366, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (35677864..35680614, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (35255134..35257884, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (35245093..35247843, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (35099613..35102363, complement)

    Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119865949 Neighboring gene phytanoyl-CoA 2-hydroxylase interacting protein Neighboring gene bone morphogenetic protein 1 Neighboring gene leucine rich repeat LGI family member 3 Neighboring gene receptor accessory protein 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in respiratory gaseous exchange by respiratory system IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in alveolar lamellar body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    surfactant protein C; pulmonary surfactant-associated protein C
    Names
    Pulmonary surfactant-associated protein C
    Pulmonary surfactant-associated proteolipid SPL(Val)
    surfactant, pulmonary-associated protein C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051829.1 Reference ROS_Cfam_1.0

      Range
      35299616..35302366 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038434634.1 → XP_038290562.1  pulmonary surfactant-associated protein C isoform X1

      UniProtKB/TrEMBL
      A0A8C0KZN9, A0A8C0TKL7, A0A8I3S9H9
      Related
      ENSCAFP00845035440.1, ENSCAFT00845045197.1
      Conserved Domains (1) summary
      smart00019
      Location:10 → 200
      SF_P; Pulmonary surfactant proteins

    2. XM_038434635.1 → XP_038290563.1  pulmonary surfactant-associated protein C isoform X2

      Conserved Domains (1) summary
      smart00019
      Location:10 → 147
      SF_P; Pulmonary surfactant proteins

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049285.1 Alternate UMICH_Zoey_3.1

      Range
      35245093..35247843 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038511044.1 → XP_038366972.1  pulmonary surfactant-associated protein C isoform X1

      Conserved Domains (1) summary
      smart00019
      Location:10 → 200
      SF_P; Pulmonary surfactant proteins

    2. XM_038511045.1 → XP_038366973.1  pulmonary surfactant-associated protein C isoform X2

      Conserved Domains (1) summary
      smart00019
      Location:10 → 147
      SF_P; Pulmonary surfactant proteins

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

      Range
      35099613..35102363 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038637319.1 → XP_038493247.1  pulmonary surfactant-associated protein C isoform X1

      Conserved Domains (1) summary
      smart00019
      Location:10 → 200
      SF_P; Pulmonary surfactant proteins

    2. XM_038637320.1 → XP_038493248.1  pulmonary surfactant-associated protein C isoform X2

      Conserved Domains (1) summary
      smart00019
      Location:10 → 147
      SF_P; Pulmonary surfactant proteins

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

      Range
      35255134..35257884 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038573075.1 → XP_038429003.1  pulmonary surfactant-associated protein C isoform X1

      UniProtKB/TrEMBL
      A0A8C0KZN9, A0A8C0TKL7, A0A8I3S9H9
      Conserved Domains (1) summary
      smart00019
      Location:10 → 200
      SF_P; Pulmonary surfactant proteins

    2. XM_038573076.1 → XP_038429004.1  pulmonary surfactant-associated protein C isoform X2

      Conserved Domains (1) summary
      smart00019
      Location:10 → 147
      SF_P; Pulmonary surfactant proteins

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      35677864..35680614 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_534578.6 → XP_534578.4  pulmonary surfactant-associated protein C isoform X1

      UniProtKB/TrEMBL
      A0A8C0KZN9, A0A8C0TKL7, A0A8I3S9H9
      Conserved Domains (1) summary
      smart00019
      Location:10 → 200
      SF_P; Pulmonary surfactant proteins

    2. XM_014107485.3 → XP_013962960.2  pulmonary surfactant-associated protein C isoform X2

      Conserved Domains (1) summary
      smart00019
      Location:10 → 147
      SF_P; Pulmonary surfactant proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P22397.1 GenPept UniProtKB/Swiss-Prot:P22397

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    Molecular Biology Databases
    Research Materials