CPNE1 copine 1 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: CPNE1provided by VGNC
Official Full Name: copine 1provided by VGNC
Primary source: VGNC:VGNC:39560
See related: Ensembl:ENSCAFG00845022102
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 24

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	24	NC_051828.1 (25247213..25282324, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	24	NC_006606.4 (24199753..24234861, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	24	NC_049245.1 (25067994..25103125, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	24	NC_049284.1 (24533545..24568660, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	24	NC_049765.1 (24628580..24663692, complement)

Chromosome 24 - NC_051828.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

ECD01784 (e-PCR)
- UniSTS:282885

ECD02844 (e-PCR)
- UniSTS:283937

SHGC-35711 (e-PCR)
- UniSTS:11126

stSG636768 (e-PCR)
- UniSTS:461179

stSG636769 (e-PCR)
- UniSTS:461180

MARC_6962-6963:992007593:3 (e-PCR)
- UniSTS:231292

MARC_6962-6963:996689875:1 (e-PCR)
- UniSTS:231292

REN58589 (e-PCR)
- UniSTS:383389

REN58602 (e-PCR)
- UniSTS:383402

REN58605 (e-PCR)
- UniSTS:383405

REN58606 (e-PCR)
- UniSTS:383406

REN58607 (e-PCR)
- UniSTS:383407

ECD04836 (e-PCR)
- UniSTS:285907

ECD04598 (e-PCR)
- UniSTS:285670

WI-14831 (e-PCR)
- UniSTS:52454

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium-dependent phospholipid binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular response to calcium ion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of tumor necrosis factor-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of canonical NF-kappaB signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: copine-1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001171749.1 → NP_001165220.1 copine-1

Status: PROVISIONAL

Source sequence(s)

JAAUVH010000376

UniProtKB/TrEMBL

A0A8C0JY93, A0A8C0PKA2, A0A8I3S2Y1, A0A8P0NAH9

Related

ENSCAFP00845030654.1, ENSCAFT00845039143.1

Conserved Domains (3) summary

cd04047
Location:138 → 245

C2B_Copine; C2 domain second repeat in Copine

cd04048
Location:6 → 124

C2A_Copine; C2 domain first repeat in Copine

cd01459
Location:251 → 509

vWA_copine_like; VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae. ...