LMOD3 leiomodin 3 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: LMOD3provided by VGNC
Official Full Name: leiomodin 3provided by VGNC
Primary source: VGNC:VGNC:42726
See related: Ensembl:ENSCAFG00845010392
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	20	NC_051824.1 (22638734..22655016)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	20	NC_006602.4 (22587390..22603662)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	20	NC_049241.1 (22746668..22762961)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	20	NC_049280.1 (22333633..22349893)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	20	NC_049761.1 (22675875..22692165)

Chromosome 20 - NC_051824.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables tropomyosin binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in muscle contraction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in myofibril assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in pointed-end actin filament capping	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in myofibril	IEA Inferred from Electronic Annotation more info	PubMed
located_in striated muscle thin filament	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: leiomodin-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051824.1 Reference ROS_Cfam_1.0

Range

22638734..22655016

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038427174.1 → XP_038283102.1 leiomodin-3 isoform X1

UniProtKB/TrEMBL

A0A8C0KIE0, A0A8I3NDA6, A0A8I3NFX9

Related

ENSCAFP00845014289.1, ENSCAFT00845018303.1

Conserved Domains (2) summary

pfam03250
Location:61 → 152

Tropomodulin

cl39015
Location:300 → 405

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_038427175.1 → XP_038283103.1 leiomodin-3 isoform X2

UniProtKB/TrEMBL

A0A8C0KIE0, A0A8I3NFX9

Conserved Domains (2) summary

pfam03250
Location:16 → 107

Tropomodulin

cl39015
Location:255 → 360

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049280.1 Alternate UMICH_Zoey_3.1

Range

22333633..22349893

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038502925.1 → XP_038358853.1 leiomodin-3 isoform X3

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049761.1 Alternate UNSW_CanFamBas_1.0

Range

22675875..22692165

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038629992.1 → XP_038485920.1 leiomodin-3 isoform X1

Conserved Domains (2) summary

pfam03250
Location:61 → 152

Tropomodulin

cl39015
Location:300 → 405

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_038629993.1 → XP_038485921.1 leiomodin-3 isoform X2

Conserved Domains (2) summary

pfam03250
Location:16 → 107

Tropomodulin

cl39015
Location:255 → 360

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049241.1 Alternate UU_Cfam_GSD_1.0

Range

22746668..22762961

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038565876.1 → XP_038421804.1 leiomodin-3 isoform X1

UniProtKB/TrEMBL

A0A8C0KIE0, A0A8I3NDA6, A0A8I3NFX9

Conserved Domains (2) summary

pfam03250
Location:61 → 152

Tropomodulin

cl39015
Location:300 → 405

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_038565877.1 → XP_038421805.1 leiomodin-3 isoform X2

UniProtKB/TrEMBL

A0A8C0KIE0, A0A8I3NFX9

Conserved Domains (2) summary

pfam03250
Location:16 → 107

Tropomodulin

cl39015
Location:255 → 360

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

22587390..22603662

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_549501.6 → XP_549501.4 leiomodin-3 isoform X1

UniProtKB/TrEMBL

A0A8C0MU41, A0A8P0SBV6, A0A8P0TM40

Conserved Domains (2) summary

pfam03250
Location:61 → 152

Tropomodulin

cl39015
Location:300 → 405

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_014121536.3 → XP_013977011.2 leiomodin-3 isoform X2

UniProtKB/TrEMBL

A0A8P0TM40

Conserved Domains (2) summary

pfam03250
Location:16 → 107

Tropomodulin

cl39015
Location:255 → 360

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...