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    FBP1 fructose-bisphosphatase 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 476299, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FBP1provided by VGNC
    Official Full Name
    fructose-bisphosphatase 1provided by VGNC
    Primary source
    VGNC:VGNC:40757
    See related
    Ensembl:ENSCAFG00845005020
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See FBP1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (72404539..72429921)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (72861998..72887376)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (72686298..72711910)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (72215481..72240826)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (71981002..72006401)

    Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene aminopeptidase O (putative) Neighboring gene uncharacterized LOC119870812 Neighboring gene uncharacterized LOC119866418 Neighboring gene fructose-bisphosphatase 2 Neighboring gene tyrosine-protein phosphatase non-receptor type 2-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables fructose 1,6-bisphosphate 1-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fructose 1,6-bisphosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fructose 6-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fructose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in gluconeogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sucrose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fructose-1,6-bisphosphatase 1
    XP_005615849.1
    XP_038322130.1
    XP_038322131.1
    XP_038382828.1
    XP_038382829.1
    XP_038447129.1
    XP_038447130.1
    XP_038510926.1
    XP_038510927.1
    XP_848306.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051805.1 Reference ROS_Cfam_1.0

      Range
      72404539..72429921
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038654998.1 → XP_038510926.1  fructose-1,6-bisphosphatase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MEJ0, A0A8C0QC07, A0A8C0R6H2, A0A8I3MZ42
      Related
      ENSCAFP00845007099.1, ENSCAFT00845009004.1
      Conserved Domains (1) summary
      cd00354
      Location:18 → 332
      FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...

    2. XM_038654999.1 → XP_038510927.1  fructose-1,6-bisphosphatase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0MRD0, A0A8I3MWI1
      Related
      ENSCAFP00845007104.1, ENSCAFT00845009009.1
      Conserved Domains (1) summary
      cd00354
      Location:1 → 279
      FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049261.1 Alternate UMICH_Zoey_3.1

      Range
      72215481..72240826
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038466202.1 → XP_038322130.1  fructose-1,6-bisphosphatase 1 isoform X1

      Conserved Domains (1) summary
      cd00354
      Location:18 → 332
      FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...

    2. XM_038466203.1 → XP_038322131.1  fructose-1,6-bisphosphatase 1 isoform X2

      Conserved Domains (1) summary
      cd00354
      Location:1 → 279
      FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

      Range
      71981002..72006401
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038591201.1 → XP_038447129.1  fructose-1,6-bisphosphatase 1 isoform X1

    2. XM_038591202.1 → XP_038447130.1  fructose-1,6-bisphosphatase 1 isoform X2

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

      Range
      72686298..72711910
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038526900.1 → XP_038382828.1  fructose-1,6-bisphosphatase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MEJ0, A0A8C0QC07, A0A8C0R6H2, A0A8I3MZ42
      Conserved Domains (1) summary
      cd00354
      Location:18 → 332
      FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...

    2. XM_038526901.1 → XP_038382829.1  fructose-1,6-bisphosphatase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0MRD0, A0A8I3MWI1
      Conserved Domains (1) summary
      cd00354
      Location:1 → 279
      FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      72861998..72887376
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_843213.3 → XP_848306.1  fructose-1,6-bisphosphatase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MEJ0, A0A8C0QC07, A0A8C0R6H2, A0A8I3MZ42
      Conserved Domains (1) summary
      cd00354
      Location:18 → 332
      FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...

    2. XM_005615792.3 → XP_005615849.1  fructose-1,6-bisphosphatase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0MRD0, A0A8I3MWI1
      Conserved Domains (1) summary
      cd00354
      Location:1 → 279
      FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...
    Nucleotide Protein
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