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    PTK2 protein tyrosine kinase 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 475108, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PTK2provided by VGNC
    Official Full Name
    protein tyrosine kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:45158
    See related
    Ensembl:ENSCAFG00845012455
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See PTK2 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    40
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (35687298..35953785, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (35161620..35427478, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (35917116..36183296, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (35407367..35673847, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (35497341..35763586, complement)

    Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098575 Neighboring gene uncharacterized LOC119864475 Neighboring gene microRNA mir-151 Neighboring gene uncharacterized LOC111098576 Neighboring gene uncharacterized LOC111098577 Neighboring gene uncharacterized LOC106559645

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Focal adhesion kinase (FAK) and mechanical stimulation negatively regulate the transition of airway smooth muscle tissues to a synthetic phenotype. Wu Y, et al. Am J Physiol Lung Cell Mol Physiol, 2016 Nov 1. PMID 27612967, Free PMC Article
    2. Nanoscale integrin cluster dynamics controls cellular mechanosensing via FAKY397 phosphorylation. Cheng B, et al. Sci Adv, 2020 Mar. PMID 32181337, Free PMC Article
    3. Src- and confinement-dependent FAK activation causes E-cadherin relaxation and β-catenin activity. Gayrard C, et al. J Cell Biol, 2018 Mar 5. PMID 29311227, Free PMC Article
    4. Non-Smad transforming growth factor-β signaling regulated by focal adhesion kinase binding the p85 subunit of phosphatidylinositol 3-kinase. Hong M, et al. J Biol Chem, 2011 May 20. PMID 21454615, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Nanoscale integrin cluster dynamics controls cellular mechanosensing via FAKY397 phosphorylation.
      Title: Nanoscale integrin cluster dynamics controls cellular mechanosensing via FAKY397 phosphorylation.
    2. Src- and confinement-dependent FAK activation causes E-cadherin relaxation and beta-catenin activity.
      Title: Src- and confinement-dependent FAK activation causes E-cadherin relaxation and β-catenin activity.
    3. The results demonstrate that the imposition of a higher mechanical load on airway smooth muscle stimulates FAK activation.
      Title: Focal adhesion kinase (FAK) and mechanical stimulation negatively regulate the transition of airway smooth muscle tissues to a synthetic phenotype.
    4. Non-Smad transforming growth factor-beta signaling regulated by focal adhesion kinase binding the p85 subunit of phosphatidylinositol 3-kinase.
      Title: Non-Smad transforming growth factor-β signaling regulated by focal adhesion kinase binding the p85 subunit of phosphatidylinositol 3-kinase.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    focal adhesion kinase 1
    Names
    PTK2 protein tyrosine kinase 2
    XP_022282477.1
    XP_038281972.1
    XP_038281983.1
    XP_038281993.1
    XP_038282001.1
    XP_038282004.1
    XP_038282008.1
    XP_038282016.1
    XP_038282017.1
    XP_038282023.1
    XP_038282034.1
    XP_038282041.1
    XP_038282042.1
    XP_038282043.1
    XP_038282045.1
    XP_038282062.1
    XP_038349291.1
    XP_038349292.1
    XP_038349293.1
    XP_038349294.1
    XP_038349295.1
    XP_038349296.1
    XP_038349297.1
    XP_038349298.1
    XP_038349299.1
    XP_038349300.1
    XP_038349301.1
    XP_038349302.1
    XP_038349303.1
    XP_038349304.1
    XP_038349305.1
    XP_038349306.1
    XP_038411540.1
    XP_038411541.1
    XP_038411542.1
    XP_038411543.1
    XP_038411545.1
    XP_038411546.1
    XP_038411547.1
    XP_038411548.1
    XP_038411549.1
    XP_038411550.1
    XP_038411551.1
    XP_038411552.1
    XP_038411553.1
    XP_038411554.1
    XP_038411556.1
    XP_038411557.1
    XP_038411558.1
    XP_038475443.1
    XP_038475444.1
    XP_038475445.1
    XP_038475446.1
    XP_038475447.1
    XP_038475448.1
    XP_038475449.1
    XP_038475450.1
    XP_038475451.1
    XP_038475452.1
    XP_038475453.1
    XP_038475454.1
    XP_038475455.1
    XP_038475456.1
    XP_038475457.1
    XP_038475458.1
    XP_038541050.1
    XP_038541051.1
    XP_038541052.1
    XP_038541053.1
    XP_038541054.1
    XP_038541055.1
    XP_038541056.1
    XP_038541057.1
    XP_038541058.1
    XP_038541059.1
    XP_038541060.1
    XP_038541061.1
    XP_038541062.1
    XP_038541063.1
    XP_038541064.1
    XP_038541065.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051817.1 Reference ROS_Cfam_1.0

      Range
      35687298..35953785 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038685132.1 → XP_038541060.1  focal adhesion kinase 1 isoform X11

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Related
      ENSCAFP00845017775.1, ENSCAFT00845022666.1
      Conserved Domains (5) summary
      cd05056
      Location:435 → 704
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:939 → 1068
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    2. XM_038685131.1 → XP_038541059.1  focal adhesion kinase 1 isoform X10

      UniProtKB/TrEMBL
      A0A8C0QNY6, A0A8C0RR56, A0A8I3RZI0, A0A8P0N4E3
      Related
      ENSCAFP00845017598.1, ENSCAFT00845022397.1
      Conserved Domains (5) summary
      cd05056
      Location:459 → 728
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:960 → 1089
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    3. XM_038685130.1 → XP_038541058.1  focal adhesion kinase 1 isoform X9

      UniProtKB/TrEMBL
      A0A8C0RR56, A0A8P0N4E3
      Conserved Domains (5) summary
      cd05056
      Location:459 → 728
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:963 → 1092
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    4. XM_038685129.1 → XP_038541057.1  focal adhesion kinase 1 isoform X8

      UniProtKB/TrEMBL
      A0A8C0RR56, A0A8P0N4E3
      Conserved Domains (5) summary
      cd05056
      Location:472 → 741
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:976 → 1105
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    5. XM_038685137.1 → XP_038541065.1  focal adhesion kinase 1 isoform X15

      UniProtKB/TrEMBL
      A0A8C0RQY8, A0A8I3NMY1
      Conserved Domains (5) summary
      cd05056
      Location:479 → 748
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:980 → 1109
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    6. XM_038685127.1 → XP_038541055.1  focal adhesion kinase 1 isoform X6

      UniProtKB/TrEMBL
      A0A8C0RQY8, A0A8I3NMY1
      Conserved Domains (5) summary
      cd05056
      Location:479 → 748
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:983 → 1112
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    7. XM_038685133.1 → XP_038541061.1  focal adhesion kinase 1 isoform X11

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Conserved Domains (5) summary
      cd05056
      Location:435 → 704
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:939 → 1068
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    8. XM_038685125.1 → XP_038541053.1  focal adhesion kinase 1 isoform X4

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Conserved Domains (5) summary
      cd05056
      Location:422 → 691
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:926 → 1055
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    9. XM_038685128.1 → XP_038541056.1  focal adhesion kinase 1 isoform X7

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Related
      ENSCAFP00845017803.1, ENSCAFT00845022699.1
      Conserved Domains (5) summary
      cd05056
      Location:421 → 690
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:922 → 1051
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    10. XM_038685126.1 → XP_038541054.1  focal adhesion kinase 1 isoform X5

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Conserved Domains (5) summary
      cd05056
      Location:421 → 690
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:925 → 1054
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    11. XM_038685123.1 → XP_038541051.1  focal adhesion kinase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I3NNS5, A0A8P0THU7
      Related
      ENSCAFP00845017467.1, ENSCAFT00845022217.1
      Conserved Domains (5) summary
      cd05056
      Location:428 → 697
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:929 → 1058
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    12. XM_038685124.1 → XP_038541052.1  focal adhesion kinase 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Related
      ENSCAFP00845017702.1, ENSCAFT00845022555.1
      Conserved Domains (5) summary
      cd05056
      Location:428 → 697
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:929 → 1058
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    13. XM_038685122.1 → XP_038541050.1  focal adhesion kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0P524, A0A8I3NDM5
      Conserved Domains (5) summary
      cd05056
      Location:428 → 697
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:932 → 1061
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    14. XM_038685134.1 → XP_038541062.1  focal adhesion kinase 1 isoform X12

      UniProtKB/TrEMBL
      A0A8C0QK80
      Conserved Domains (4) summary
      cd05056
      Location:320 → 589
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:7 → 143
      B41; Band 4.1 homologues
      cd13190
      Location:139 → 249
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:824 → 953
      Focal_AT; Focal adhesion targeting region

    15. XM_038685135.1 → XP_038541063.1  focal adhesion kinase 1 isoform X13

      Conserved Domains (3) summary
      cd05056
      Location:121 → 390
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      pfam03623
      Location:625 → 754
      Focal_AT; Focal adhesion targeting region
      cl17171
      Location:1 → 50
      PH-like; Pleckstrin homology-like domain

    16. XM_038685136.1 → XP_038541064.1  focal adhesion kinase 1 isoform X14

      Conserved Domains (1) summary
      pfam03623
      Location:229 → 358
      Focal_AT; Focal adhesion targeting region

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049273.1 Alternate UMICH_Zoey_3.1

      Range
      35407367..35673847 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038493373.1 → XP_038349301.1  focal adhesion kinase 1 isoform X11

      Conserved Domains (5) summary
      cd05056
      Location:435 → 704
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:939 → 1068
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    2. XM_038493372.1 → XP_038349300.1  focal adhesion kinase 1 isoform X10

      Conserved Domains (5) summary
      cd05056
      Location:459 → 728
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:960 → 1089
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    3. XM_038493371.1 → XP_038349299.1  focal adhesion kinase 1 isoform X9

      Conserved Domains (5) summary
      cd05056
      Location:459 → 728
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:963 → 1092
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    4. XM_038493370.1 → XP_038349298.1  focal adhesion kinase 1 isoform X8

      Conserved Domains (5) summary
      cd05056
      Location:472 → 741
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:976 → 1105
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    5. XM_038493378.1 → XP_038349306.1  focal adhesion kinase 1 isoform X15

      Conserved Domains (5) summary
      cd05056
      Location:479 → 748
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:980 → 1109
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    6. XM_038493368.1 → XP_038349296.1  focal adhesion kinase 1 isoform X6

      Conserved Domains (5) summary
      cd05056
      Location:479 → 748
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:983 → 1112
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    7. XM_038493374.1 → XP_038349302.1  focal adhesion kinase 1 isoform X11

      Conserved Domains (5) summary
      cd05056
      Location:435 → 704
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:939 → 1068
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    8. XM_038493366.1 → XP_038349294.1  focal adhesion kinase 1 isoform X4

      Conserved Domains (5) summary
      cd05056
      Location:422 → 691
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:926 → 1055
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    9. XM_038493369.1 → XP_038349297.1  focal adhesion kinase 1 isoform X7

      Conserved Domains (5) summary
      cd05056
      Location:421 → 690
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:922 → 1051
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    10. XM_038493367.1 → XP_038349295.1  focal adhesion kinase 1 isoform X5

      Conserved Domains (5) summary
      cd05056
      Location:421 → 690
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:925 → 1054
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    11. XM_038493364.1 → XP_038349292.1  focal adhesion kinase 1 isoform X2

      Conserved Domains (5) summary
      cd05056
      Location:428 → 697
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:929 → 1058
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    12. XM_038493365.1 → XP_038349293.1  focal adhesion kinase 1 isoform X3

      Conserved Domains (5) summary
      cd05056
      Location:428 → 697
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:929 → 1058
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    13. XM_038493363.1 → XP_038349291.1  focal adhesion kinase 1 isoform X1

      Conserved Domains (5) summary
      cd05056
      Location:428 → 697
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:932 → 1061
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    14. XM_038493375.1 → XP_038349303.1  focal adhesion kinase 1 isoform X12

      Conserved Domains (4) summary
      cd05056
      Location:320 → 589
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:7 → 143
      B41; Band 4.1 homologues
      cd13190
      Location:139 → 249
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:824 → 953
      Focal_AT; Focal adhesion targeting region

    15. XM_038493376.1 → XP_038349304.1  focal adhesion kinase 1 isoform X13

      Conserved Domains (3) summary
      cd05056
      Location:121 → 390
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      pfam03623
      Location:625 → 754
      Focal_AT; Focal adhesion targeting region
      cl17171
      Location:1 → 50
      PH-like; Pleckstrin homology-like domain

    16. XM_038493377.1 → XP_038349305.1  focal adhesion kinase 1 isoform X14

      Conserved Domains (1) summary
      pfam03623
      Location:229 → 358
      Focal_AT; Focal adhesion targeting region

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

      Range
      35497341..35763586 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038619525.1 → XP_038475453.1  focal adhesion kinase 1 isoform X11

      Conserved Domains (5) summary
      cd05056
      Location:435 → 704
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:939 → 1068
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    2. XM_038619524.1 → XP_038475452.1  focal adhesion kinase 1 isoform X10

      Conserved Domains (5) summary
      cd05056
      Location:459 → 728
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:960 → 1089
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    3. XM_038619523.1 → XP_038475451.1  focal adhesion kinase 1 isoform X9

      Conserved Domains (5) summary
      cd05056
      Location:459 → 728
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:963 → 1092
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    4. XM_038619522.1 → XP_038475450.1  focal adhesion kinase 1 isoform X8

      Conserved Domains (5) summary
      cd05056
      Location:472 → 741
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:976 → 1105
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    5. XM_038619530.1 → XP_038475458.1  focal adhesion kinase 1 isoform X15

      Conserved Domains (5) summary
      cd05056
      Location:479 → 748
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:980 → 1109
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    6. XM_038619520.1 → XP_038475448.1  focal adhesion kinase 1 isoform X6

      Conserved Domains (5) summary
      cd05056
      Location:479 → 748
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:983 → 1112
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    7. XM_038619526.1 → XP_038475454.1  focal adhesion kinase 1 isoform X11

      Conserved Domains (5) summary
      cd05056
      Location:435 → 704
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:939 → 1068
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    8. XM_038619518.1 → XP_038475446.1  focal adhesion kinase 1 isoform X4

      Conserved Domains (5) summary
      cd05056
      Location:422 → 691
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:926 → 1055
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    9. XM_038619521.1 → XP_038475449.1  focal adhesion kinase 1 isoform X7

      Conserved Domains (5) summary
      cd05056
      Location:421 → 690
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:922 → 1051
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    10. XM_038619519.1 → XP_038475447.1  focal adhesion kinase 1 isoform X5

      Conserved Domains (5) summary
      cd05056
      Location:421 → 690
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:925 → 1054
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    11. XM_038619516.1 → XP_038475444.1  focal adhesion kinase 1 isoform X2

      Conserved Domains (5) summary
      cd05056
      Location:428 → 697
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:929 → 1058
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    12. XM_038619517.1 → XP_038475445.1  focal adhesion kinase 1 isoform X3

      Conserved Domains (5) summary
      cd05056
      Location:428 → 697
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:929 → 1058
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    13. XM_038619515.1 → XP_038475443.1  focal adhesion kinase 1 isoform X1

      Conserved Domains (5) summary
      cd05056
      Location:428 → 697
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:932 → 1061
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    14. XM_038619527.1 → XP_038475455.1  focal adhesion kinase 1 isoform X12

      Conserved Domains (4) summary
      cd05056
      Location:320 → 589
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:7 → 143
      B41; Band 4.1 homologues
      cd13190
      Location:139 → 249
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:824 → 953
      Focal_AT; Focal adhesion targeting region

    15. XM_038619528.1 → XP_038475456.1  focal adhesion kinase 1 isoform X13

      Conserved Domains (3) summary
      cd05056
      Location:121 → 390
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      pfam03623
      Location:625 → 754
      Focal_AT; Focal adhesion targeting region
      cl17171
      Location:1 → 50
      PH-like; Pleckstrin homology-like domain

    16. XM_038619529.1 → XP_038475457.1  focal adhesion kinase 1 isoform X14

      Conserved Domains (1) summary
      pfam03623
      Location:229 → 358
      Focal_AT; Focal adhesion targeting region

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

      Range
      35917116..36183296 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038555624.1 → XP_038411552.1  focal adhesion kinase 1 isoform X11

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Conserved Domains (5) summary
      cd05056
      Location:435 → 704
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:939 → 1068
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    2. XM_038555623.1 → XP_038411551.1  focal adhesion kinase 1 isoform X10

      UniProtKB/TrEMBL
      A0A8C0RR56, A0A8P0N4E3

    3. XM_038555622.1 → XP_038411550.1  focal adhesion kinase 1 isoform X9

      UniProtKB/TrEMBL
      A0A8C0RR56, A0A8P0N4E3

    4. XM_038555619.1 → XP_038411547.1  focal adhesion kinase 1 isoform X19

      UniProtKB/TrEMBL
      A0A8C0RR56, A0A8P0N4E3

    5. XM_038555621.1 → XP_038411549.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8C0RQY8, A0A8I3NMY1

    6. XM_038555620.1 → XP_038411548.1  focal adhesion kinase 1 isoform X20

      UniProtKB/TrEMBL
      A0A8C0RQY8, A0A8I3NMY1

    7. XM_038555617.1 → XP_038411545.1  focal adhesion kinase 1 isoform X17

      UniProtKB/TrEMBL
      A0A8C0RR56, A0A8P0N4E3

    8. XM_038555614.1 → XP_038411542.1  focal adhesion kinase 1 isoform X8

      UniProtKB/TrEMBL
      A0A8C0RR56, A0A8P0N4E3

    9. XM_038555618.1 → XP_038411546.1  focal adhesion kinase 1 isoform X18

      UniProtKB/TrEMBL
      A0A8C0RQY8, A0A8I3NMY1

    10. XM_038555615.1 → XP_038411543.1  focal adhesion kinase 1 isoform X16

      UniProtKB/TrEMBL
      A0A8C0RQY8, A0A8I3NMY1

    11. XM_038555613.1 → XP_038411541.1  focal adhesion kinase 1 isoform X15

      UniProtKB/TrEMBL
      A0A8C0RQY8, A0A8I3NMY1

    12. XM_038555612.1 → XP_038411540.1  focal adhesion kinase 1 isoform X6

      UniProtKB/TrEMBL
      A0A8C0RQY8, A0A8I3NMY1

    13. XM_038555625.1 → XP_038411553.1  focal adhesion kinase 1 isoform X11

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Conserved Domains (5) summary
      cd05056
      Location:435 → 704
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:939 → 1068
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    14. XM_038555626.1 → XP_038411554.1  focal adhesion kinase 1 isoform X12

      UniProtKB/TrEMBL
      A0A8C0QK80
      Conserved Domains (4) summary
      cd05056
      Location:320 → 589
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:7 → 143
      B41; Band 4.1 homologues
      cd13190
      Location:139 → 249
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:824 → 953
      Focal_AT; Focal adhesion targeting region

    15. XM_038555629.1 → XP_038411557.1  focal adhesion kinase 1 isoform X13

      Conserved Domains (3) summary
      cd05056
      Location:121 → 390
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      pfam03623
      Location:625 → 754
      Focal_AT; Focal adhesion targeting region
      cl17171
      Location:1 → 50
      PH-like; Pleckstrin homology-like domain

    16. XM_038555630.1 → XP_038411558.1  focal adhesion kinase 1 isoform X14

      Conserved Domains (1) summary
      pfam03623
      Location:229 → 358
      Focal_AT; Focal adhesion targeting region

    17. XM_038555628.1 → XP_038411556.1  focal adhesion kinase 1 isoform X22

      UniProtKB/TrEMBL
      A0A8C0QBP4

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      35161620..35427478 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038426113.1 → XP_038282041.1  focal adhesion kinase 1 isoform X11

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Conserved Domains (5) summary
      cd05056
      Location:435 → 704
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:939 → 1068
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    2. XM_038426106.1 → XP_038282034.1  focal adhesion kinase 1 isoform X10

      UniProtKB/TrEMBL
      A0A8C0QNY6, A0A8C0RR56, A0A8I3RZI0, A0A8P0N4E3
      Conserved Domains (5) summary
      cd05056
      Location:459 → 728
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:960 → 1089
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    3. XM_038426095.1 → XP_038282023.1  focal adhesion kinase 1 isoform X9

      UniProtKB/TrEMBL
      A0A8C0RR56, A0A8P0N4E3
      Conserved Domains (5) summary
      cd05056
      Location:459 → 728
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:963 → 1092
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    4. XM_038426089.1 → XP_038282017.1  focal adhesion kinase 1 isoform X8

      UniProtKB/TrEMBL
      A0A8C0RR56, A0A8P0N4E3
      Conserved Domains (5) summary
      cd05056
      Location:472 → 741
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:976 → 1105
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    5. XM_038426134.1 → XP_038282062.1  focal adhesion kinase 1 isoform X15

      UniProtKB/TrEMBL
      A0A8C0RQY8, A0A8I3NMY1
      Conserved Domains (5) summary
      cd05056
      Location:479 → 748
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:980 → 1109
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    6. XM_038426080.1 → XP_038282008.1  focal adhesion kinase 1 isoform X6

      UniProtKB/TrEMBL
      A0A8C0RQY8, A0A8I3NMY1
      Conserved Domains (5) summary
      cd05056
      Location:479 → 748
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80 → 302
      B41; Band 4.1 homologues
      cd13190
      Location:298 → 408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:983 → 1112
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:79 → 174
      FERM_N_2; FERM N-terminal domain

    7. XM_038426114.1 → XP_038282042.1  focal adhesion kinase 1 isoform X11

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Conserved Domains (5) summary
      cd05056
      Location:435 → 704
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:939 → 1068
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    8. XM_038426073.1 → XP_038282001.1  focal adhesion kinase 1 isoform X4

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Conserved Domains (5) summary
      cd05056
      Location:422 → 691
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:926 → 1055
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    9. XM_038426088.1 → XP_038282016.1  focal adhesion kinase 1 isoform X7

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Conserved Domains (5) summary
      cd05056
      Location:421 → 690
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:922 → 1051
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    10. XM_038426076.1 → XP_038282004.1  focal adhesion kinase 1 isoform X5

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Conserved Domains (5) summary
      cd05056
      Location:421 → 690
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:925 → 1054
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    11. XM_038426055.1 → XP_038281983.1  focal adhesion kinase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I3NNS5, A0A8P0THU7
      Conserved Domains (5) summary
      cd05056
      Location:428 → 697
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:929 → 1058
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    12. XM_038426065.1 → XP_038281993.1  focal adhesion kinase 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I3NNS5
      Conserved Domains (5) summary
      cd05056
      Location:428 → 697
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:929 → 1058
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    13. XM_038426044.1 → XP_038281972.1  focal adhesion kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0P524, A0A8I3NDM5
      Conserved Domains (5) summary
      cd05056
      Location:428 → 697
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36 → 258
      B41; Band 4.1 homologues
      cd13190
      Location:254 → 364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:932 → 1061
      Focal_AT; Focal adhesion targeting region
      pfam18038
      Location:35 → 130
      FERM_N_2; FERM N-terminal domain

    14. XM_038426115.1 → XP_038282043.1  focal adhesion kinase 1 isoform X12

      UniProtKB/TrEMBL
      A0A8C0QK80
      Conserved Domains (4) summary
      cd05056
      Location:320 → 589
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:7 → 143
      B41; Band 4.1 homologues
      cd13190
      Location:139 → 249
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:824 → 953
      Focal_AT; Focal adhesion targeting region

    15. XM_038426117.1 → XP_038282045.1  focal adhesion kinase 1 isoform X13

      Conserved Domains (3) summary
      cd05056
      Location:121 → 390
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      pfam03623
      Location:625 → 754
      Focal_AT; Focal adhesion targeting region
      cl17171
      Location:1 → 50
      PH-like; Pleckstrin homology-like domain

    16. XM_022426769.2 → XP_022282477.1  focal adhesion kinase 1 isoform X14

      Conserved Domains (1) summary
      pfam03623
      Location:229 → 358
      Focal_AT; Focal adhesion targeting region
    Nucleotide Protein
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