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    MTAP methylthioadenosine phosphorylase [ Canis lupus familiaris (dog) ]

    Gene ID: 474729, updated on 5-Mar-2024

    Summary

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    Official Symbol
    MTAPprovided by VGNC
    Official Full Name
    methylthioadenosine phosphorylaseprovided by VGNC
    Primary source
    VGNC:VGNC:56069
    See related
    Ensembl:ENSCAFG00845016288
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See MTAP in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 11 NC_051815.1 (42090758..42142952)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 11 NC_006593.4 (39820541..39872745)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 11 NC_049232.1 (41262101..41314256)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 11 NC_049271.1 (40760953..40813082)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 11 NC_049752.1 (40648752..40701001)

    Chromosome 11 - NC_051815.1Genomic Context describing neighboring genes Neighboring gene interferon epsilon Neighboring gene microRNA mir-31 Neighboring gene uncharacterized LOC119873924 Neighboring gene uncharacterized LOC111098066 Neighboring gene uncharacterized LOC119873925 Neighboring gene cyclin dependent kinase inhibitor 2B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables S-methyl-5-thioadenosine phosphorylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-methionine salvage from methylthioadenosine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nucleoside metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    S-methyl-5'-thioadenosine phosphorylase
    XP_013973265.1
    XP_038346342.1
    XP_038346343.1
    XP_038408456.1
    XP_038408457.1
    XP_038472317.1
    XP_038472318.1
    XP_038517358.1
    XP_038537792.1
    XP_038537793.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051815.1 Reference ROS_Cfam_1.0

      Range
      42090758..42142952
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038681864.1 → XP_038537792.1  S-methyl-5'-thioadenosine phosphorylase isoform X1

      UniProtKB/TrEMBL
      A0A8C0MV73, A0A8I3NWM2, A0A8P0TQU2
      Related
      ENSCAFP00845022769.1, ENSCAFT00845028938.1
      Conserved Domains (1) summary
      cd09010
      Location:49 → 292
      MTAP_SsMTAPII_like_MTIP; 5'-deoxy-5'-methylthioadenosine phosphorylases (MTAP) similar to Sulfolobus solfataricus MTAPII and Pseudomonas aeruginosa PAO1 5'-methylthioinosine phosphorylase (MTIP)

    2. XM_038681865.1 → XP_038537793.1  S-methyl-5'-thioadenosine phosphorylase isoform X2

      UniProtKB/TrEMBL
      A0A8C0KMQ7, A0A8C0Q288, A0A8C0RHD8, A0A8I3NWN6
      Related
      ENSCAFP00845022794.1, ENSCAFT00845028975.1
      Conserved Domains (1) summary
      cd09010
      Location:12 → 255
      MTAP_SsMTAPII_like_MTIP; 5'-deoxy-5'-methylthioadenosine phosphorylases (MTAP) similar to Sulfolobus solfataricus MTAPII and Pseudomonas aeruginosa PAO1 5'-methylthioinosine phosphorylase (MTIP)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049271.1 Alternate UMICH_Zoey_3.1

      Range
      40760953..40813082
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038490414.1 → XP_038346342.1  S-methyl-5'-thioadenosine phosphorylase isoform X1

      Conserved Domains (1) summary
      cd09010
      Location:49 → 292
      MTAP_SsMTAPII_like_MTIP; 5'-deoxy-5'-methylthioadenosine phosphorylases (MTAP) similar to Sulfolobus solfataricus MTAPII and Pseudomonas aeruginosa PAO1 5'-methylthioinosine phosphorylase (MTIP)

    2. XM_038490415.1 → XP_038346343.1  S-methyl-5'-thioadenosine phosphorylase isoform X2

      Conserved Domains (1) summary
      cd09010
      Location:12 → 255
      MTAP_SsMTAPII_like_MTIP; 5'-deoxy-5'-methylthioadenosine phosphorylases (MTAP) similar to Sulfolobus solfataricus MTAPII and Pseudomonas aeruginosa PAO1 5'-methylthioinosine phosphorylase (MTIP)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049752.1 Alternate UNSW_CanFamBas_1.0

      Range
      40648752..40701001
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038616389.1 → XP_038472317.1  S-methyl-5'-thioadenosine phosphorylase isoform X1

      Conserved Domains (1) summary
      cd09010
      Location:49 → 292
      MTAP_SsMTAPII_like_MTIP; 5'-deoxy-5'-methylthioadenosine phosphorylases (MTAP) similar to Sulfolobus solfataricus MTAPII and Pseudomonas aeruginosa PAO1 5'-methylthioinosine phosphorylase (MTIP)

    2. XM_038616390.1 → XP_038472318.1  S-methyl-5'-thioadenosine phosphorylase isoform X2

      Conserved Domains (1) summary
      cd09010
      Location:12 → 255
      MTAP_SsMTAPII_like_MTIP; 5'-deoxy-5'-methylthioadenosine phosphorylases (MTAP) similar to Sulfolobus solfataricus MTAPII and Pseudomonas aeruginosa PAO1 5'-methylthioinosine phosphorylase (MTIP)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049232.1 Alternate UU_Cfam_GSD_1.0

      Range
      41262101..41314256
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038552528.1 → XP_038408456.1  S-methyl-5'-thioadenosine phosphorylase isoform X1

      UniProtKB/TrEMBL
      A0A8C0MV73, A0A8I3NWM2, A0A8P0TQU2
      Conserved Domains (1) summary
      cd09010
      Location:49 → 292
      MTAP_SsMTAPII_like_MTIP; 5'-deoxy-5'-methylthioadenosine phosphorylases (MTAP) similar to Sulfolobus solfataricus MTAPII and Pseudomonas aeruginosa PAO1 5'-methylthioinosine phosphorylase (MTIP)

    2. XM_038552529.1 → XP_038408457.1  S-methyl-5'-thioadenosine phosphorylase isoform X2

      UniProtKB/TrEMBL
      A0A8C0KMQ7, A0A8C0Q288, A0A8C0RHD8, A0A8I3NWN6
      Conserved Domains (1) summary
      cd09010
      Location:12 → 255
      MTAP_SsMTAPII_like_MTIP; 5'-deoxy-5'-methylthioadenosine phosphorylases (MTAP) similar to Sulfolobus solfataricus MTAPII and Pseudomonas aeruginosa PAO1 5'-methylthioinosine phosphorylase (MTIP)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006593.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      39820541..39872745
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014117790.3 → XP_013973265.1  S-methyl-5'-thioadenosine phosphorylase isoform X1

      UniProtKB/TrEMBL
      A0A8C0MV73, A0A8I3NWM2, A0A8P0TQU2
      Conserved Domains (1) summary
      cd09010
      Location:49 → 292
      MTAP_SsMTAPII_like_MTIP; 5'-deoxy-5'-methylthioadenosine phosphorylases (MTAP) similar to Sulfolobus solfataricus MTAPII and Pseudomonas aeruginosa PAO1 5'-methylthioinosine phosphorylase (MTIP)

    2. XM_038661430.1 → XP_038517358.1  S-methyl-5'-thioadenosine phosphorylase isoform X2

      UniProtKB/TrEMBL
      A0A8C0KMQ7, A0A8C0Q288, A0A8C0RHD8, A0A8I3NWN6
      Conserved Domains (1) summary
      cd09010
      Location:12 → 255
      MTAP_SsMTAPII_like_MTIP; 5'-deoxy-5'-methylthioadenosine phosphorylases (MTAP) similar to Sulfolobus solfataricus MTAPII and Pseudomonas aeruginosa PAO1 5'-methylthioinosine phosphorylase (MTIP)
    Nucleotide Protein
    Heading Accession and Version

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