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    RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase [ Canis lupus familiaris (dog) ]

    Gene ID: 474524, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RTCBprovided by VGNC
    Official Full Name
    RNA 2',3'-cyclic phosphate and 5'-OH ligaseprovided by VGNC
    Primary source
    VGNC:VGNC:49844
    See related
    Ensembl:ENSCAFG00845011277
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See RTCB in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (31853471..31876814)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (30993808..31017083)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (32068649..32091998)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (31593115..31622657)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (31882145..31905453)

    Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene synapsin III Neighboring gene uncharacterized LOC119873638 Neighboring gene F-box protein 7 Neighboring gene BPI fold containing family C Neighboring gene uncharacterized LOC111097670 Neighboring gene achaete-scute family bHLH transcription factor 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA ligase (ATP) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in tRNA splicing, via endonucleolytic cleavage and ligation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of tRNA-splicing ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RNA-splicing ligase RtcB homolog
    Names
    tRNA-splicing ligase RtcB homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051814.1 Reference ROS_Cfam_1.0

      Range
      31853471..31876814
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038680058.1 → XP_038535986.1  RNA-splicing ligase RtcB homolog isoform X1

      UniProtKB/TrEMBL
      A0A8C0JVM5, A0A8C0RZD5, A0A8C0SYW0, A0A8I3PDZ7
      Related
      ENSCAFP00845015666.1, ENSCAFT00845019997.1
      Conserved Domains (1) summary
      pfam01139
      Location:68 → 505
      RtcB; tRNA-splicing ligase RtcB

    2. XM_038680059.1 → XP_038535987.1  RNA-splicing ligase RtcB homolog isoform X2

      UniProtKB/TrEMBL
      A0A8P0NQG3
      Conserved Domains (1) summary
      pfam01139
      Location:13 → 450
      RtcB; tRNA-splicing ligase RtcB

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049270.1 Alternate UMICH_Zoey_3.1

      Range
      31593115..31622657
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038488806.1 → XP_038344734.1  RNA-splicing ligase RtcB homolog isoform X1

      Conserved Domains (1) summary
      pfam01139
      Location:68 → 505
      RtcB; tRNA-splicing ligase RtcB

    2. XM_038488807.1 → XP_038344735.1  RNA-splicing ligase RtcB homolog isoform X2

      Conserved Domains (1) summary
      pfam01139
      Location:13 → 450
      RtcB; tRNA-splicing ligase RtcB

    RNA

    1. XR_005331994.1 RNA Sequence

    2. XR_005331991.1 RNA Sequence

    3. XR_005331993.1 RNA Sequence

    4. XR_005331992.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

      Range
      31882145..31905453
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038614685.1 → XP_038470613.1  RNA-splicing ligase RtcB homolog isoform X1

      Conserved Domains (1) summary
      pfam01139
      Location:68 → 505
      RtcB; tRNA-splicing ligase RtcB

    2. XM_038614686.1 → XP_038470614.1  RNA-splicing ligase RtcB homolog isoform X2

      Conserved Domains (1) summary
      pfam01139
      Location:13 → 450
      RtcB; tRNA-splicing ligase RtcB

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

      Range
      32068649..32091998
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038550762.1 → XP_038406690.1  RNA-splicing ligase RtcB homolog isoform X1

      UniProtKB/TrEMBL
      A0A8C0JVM5, A0A8C0RZD5, A0A8C0SYW0, A0A8I3PDZ7
      Conserved Domains (1) summary
      pfam01139
      Location:68 → 505
      RtcB; tRNA-splicing ligase RtcB

    2. XM_038550763.1 → XP_038406691.1  RNA-splicing ligase RtcB homolog isoform X2

      UniProtKB/TrEMBL
      A0A8P0NQG3
      Conserved Domains (1) summary
      pfam01139
      Location:13 → 450
      RtcB; tRNA-splicing ligase RtcB

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      30993808..31017083
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_531754.8 → XP_531754.2  RNA-splicing ligase RtcB homolog isoform X1

      See identical proteins and their annotated locations for XP_531754.2

      UniProtKB/TrEMBL
      A0A8C0JVM5, A0A8C0RZD5, A0A8C0SYW0, A0A8I3PDZ7
      Conserved Domains (1) summary
      pfam01139
      Location:68 → 505
      RtcB; tRNA-splicing ligase RtcB

    2. XM_022424506.2 → XP_022280214.1  RNA-splicing ligase RtcB homolog isoform X2

      UniProtKB/TrEMBL
      A0A8P0NQG3
      Conserved Domains (1) summary
      pfam01139
      Location:13 → 450
      RtcB; tRNA-splicing ligase RtcB
    Nucleotide Protein
    Heading Accession and Version

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