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    COX5A cytochrome c oxidase subunit 5A [ Bos taurus (domestic cattle) ]

    Gene ID: 444878, updated on 4-Oct-2024

    Summary

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    Official Symbol
    COX5Aprovided by VGNC
    Official Full Name
    cytochrome c oxidase subunit 5Aprovided by VGNC
    Primary source
    VGNC:VGNC:27636
    See related
    BGD:BT26852; Ensembl:ENSBTAG00000017267
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See COX5A in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 21 NC_037348.1 (33765160..33776139)

    Chromosome 21 - NC_037348.1Genomic Context describing neighboring genes Neighboring gene secretory carrier membrane protein 5 Neighboring gene ribonuclease P and MRP subunit p25 Neighboring gene family with sequence similarity 219 member B Neighboring gene mannose phosphate isomerase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037348.1 Chromosome 21 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Amino acid sequence of subunit V of bovine heart cytochrome oxidase, the heme alpha-containing subunit. Tanaka M, et al. J Biol Chem, 1979 May 25. PMID 220224
    2. Tissue-specific differences between heart and liver cytochrome c oxidase. Yanamura W, et al. Biochemistry, 1988 Jun 28. PMID 2844245
    3. X-ray structure of azide-bound fully oxidized cytochrome c oxidase from bovine heart at 2.9 A resolution. Fei MJ, et al. Acta Crystallogr D Biol Crystallogr, 2000 May. PMID 10771420
    4. Structure analysis of bovine heart cytochrome c oxidase at 2.8 A resolution. Tomizaki T, et al. Acta Crystallogr D Biol Crystallogr, 1999 Jan. PMID 10089392
    5. The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A. Tsukihara T, et al. Science, 1996 May 24. PMID 8638158

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC133649

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, cytochrome c to oxygen IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytochrome c oxidase subunit 5A, mitochondrial
    Names
    cytochrome c oxidase polypeptide Va
    cytochrome c oxidase subunit Va
    mitochondrial cytochrome c oxidase subunit 5a
    NP_001002891.1
    XP_005221971.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002891.1 → NP_001002891.1  cytochrome c oxidase subunit 5A, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001002891.1

      Status: PROVISIONAL

      Source sequence(s)
      AY528254
      UniProtKB/Swiss-Prot
      P00426, Q32LF6, Q6QRN2
      Related
      ENSBTAP00000022949.3, ENSBTAT00000022949.5
      Conserved Domains (1) summary
      cd00923
      Location:47 → 148
      Cyt_c_Oxidase_Va; Cytochrome c oxidase subunit Va. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037348.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      33765160..33776139
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005221914.3 → XP_005221971.1  cytochrome c oxidase subunit 5A, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_005221971.1

      UniProtKB/Swiss-Prot
      P00426, Q32LF6, Q6QRN2
      Conserved Domains (1) summary
      cd00923
      Location:47 → 148
      Cyt_c_Oxidase_Va; Cytochrome c oxidase subunit Va. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P00426.2 GenPept UniProtKB/Swiss-Prot:P00426

    Gene LinkOut

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