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    INHBA inhibin subunit beta A [ Ovis aries (sheep) ]

    Gene ID: 443524, updated on 5-Mar-2024

    Summary

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    Gene symbol
    INHBA
    Gene description
    inhibin subunit beta A
    See related
    EnsemblRapid:ENSOARG00020000159
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    See INHBA in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 4 NC_056057.1 (80953451..80978011)

    Chromosome 4 - NC_056057.1Genomic Context describing neighboring genes Neighboring gene GLI family zinc finger 3 Neighboring gene tropomyosin alpha-3 chain Neighboring gene uncharacterized LOC132659753 Neighboring gene uncharacterized LOC114114534

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056057.1 Chromosome 4 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Exploration the role of INHBA in Hu sheep granulosa cells using RNA-Seq. Bao Y, et al. Theriogenology, 2023 Feb. PMID 36525859
    2. Tissue-specific variation in the length of the 5' untranslated region of the beta A-inhibin mRNA in sheep. Fleming JS, et al. Mol Reprod Dev, 1995 Jan. PMID 7702862
    3. Isolation of inhibin from ovine follicular fluid. Leversha LJ, et al. J Endocrinol, 1987 May. PMID 3585232

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Exploration the role of INHBA in Hu sheep granulosa cells using RNA-Seq.
      Title: Exploration the role of INHBA in Hu sheep granulosa cells using RNA-Seq.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables growth factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inhibin beta A chain
    Names
    activin beta-A chain
    inhibin beta A subunit
    inhibin, beta A (activin A, activin AB alpha polypeptide)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009458.1 → NP_001009458.1  inhibin beta A chain precursor

      Status: PROVISIONAL

      Source sequence(s)
      L19218
      UniProtKB/Swiss-Prot
      P43032
      UniProtKB/TrEMBL
      A2ICA4
      Conserved Domains (2) summary
      smart00204
      Location:320 → 425
      TGFB; Transforming growth factor-beta (TGF-beta) family
      pfam00688
      Location:56 → 242
      TGFb_propeptide; TGF-beta propeptide

    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056057.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      80953451..80978011
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027968361.3 → XP_027824162.2  inhibin beta A chain isoform X1

      UniProtKB/TrEMBL
      A2ICA4, W5Q7R4
      Conserved Domains (2) summary
      cd19404
      Location:318 → 425
      TGF_beta_INHBA; transforming growth factor beta (TGF-beta) like domain found in inhibin beta A chain (INHBA) and similar proteins
      cl02928
      Location:56 → 242
      TGFb_propeptide; TGF-beta propeptide

    2. XM_027968362.3 → XP_027824163.2  inhibin beta A chain isoform X1

      UniProtKB/TrEMBL
      A2ICA4, W5Q7R4
      Related
      ENSOARP00020000124.2, ENSOART00020000187.2
      Conserved Domains (2) summary
      cd19404
      Location:318 → 425
      TGF_beta_INHBA; transforming growth factor beta (TGF-beta) like domain found in inhibin beta A chain (INHBA) and similar proteins
      cl02928
      Location:56 → 242
      TGFb_propeptide; TGF-beta propeptide

    3. XM_042248314.2 → XP_042104248.1  inhibin beta A chain isoform X1

      UniProtKB/TrEMBL
      A2ICA4, W5Q7R4
      Conserved Domains (2) summary
      cd19404
      Location:318 → 425
      TGF_beta_INHBA; transforming growth factor beta (TGF-beta) like domain found in inhibin beta A chain (INHBA) and similar proteins
      cl02928
      Location:56 → 242
      TGFb_propeptide; TGF-beta propeptide
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P43032.1 GenPept UniProtKB/Swiss-Prot:P43032

    Gene LinkOut

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    Research Materials