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    BCAT1 branched chain amino acid transaminase 1 [ Ovis aries (sheep) ]

    Gene ID: 443485, updated on 18-Sep-2024

    Summary

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    Gene symbol
    BCAT1
    Gene description
    branched chain amino acid transaminase 1
    See related
    EnsemblRapid:ENSOARG00020004542
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    See BCAT1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 3 NC_056056.1 (190675754..190797952)

    Chromosome 3 - NC_056056.1Genomic Context describing neighboring genes Neighboring gene dynein axonemal intermediate chain 7 Neighboring gene large ribosomal subunit protein uL22-like Neighboring gene inositol 1,4,5-triphosphate receptor associated 2 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene SRY-box transcription factor 5 Neighboring gene transfer RNA serine (anticodon GGA)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056056.1 Chromosome 3 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sheep cytosolic branched-chain amino acid aminotransferase: cDNA cloning, primary structure and molecular modelling and its unique expression in muscles. Bonfils J, et al. Biochim Biophys Acta, 2000 Nov 15. PMID 11072075
    2. Assignment of BCAT1, the gene encoding cytosolic branched chain aminotransferase, to sheep chromosome band 3q33 and to cattle and goat chromosome bands 5q33 by in situ hybridization. Hayes H, et al. Cytogenet Cell Genet, 2000. PMID 11060454

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables branched-chain-amino-acid transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-leucine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in L-valine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    branched-chain-amino-acid aminotransferase, cytosolic
    Names
    BCAT(c)
    branched chain aminotransferase 1, cytosolic
    cytosolic branched-chain amino acid aminotransferase
    NP_001009444.1
    XP_012015255.3
    XP_042101165.1
    XP_042101167.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009444.1 → NP_001009444.1  branched-chain-amino-acid aminotransferase, cytosolic

      See identical proteins and their annotated locations for NP_001009444.1

      Status: PROVISIONAL

      Source sequence(s)
      AF184916
      UniProtKB/Swiss-Prot
      Q9GKM4
      Related
      ENSOARP00020034610.1, ENSOART00020066162.1
      Conserved Domains (2) summary
      PRK13357
      Location:38 → 385
      PRK13357; branched-chain amino acid aminotransferase; Provisional
      cd01557
      Location:79 → 374
      BCAT_beta_family; BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and ...

    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056056.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      190675754..190797952
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012159865.4 → XP_012015255.3  branched-chain-amino-acid aminotransferase, cytosolic isoform X3

      UniProtKB/TrEMBL
      W5QFT5
      Related
      ENSOARP00020006110.2, ENSOART00020007387.2
      Conserved Domains (1) summary
      PRK13357
      Location:39 → 386
      PRK13357; branched-chain amino acid aminotransferase; Provisional

    2. XM_042245231.2 → XP_042101165.1  branched-chain-amino-acid aminotransferase, cytosolic isoform X1

      Related
      ENSOARP00020006174.2, ENSOART00020007461.2
      Conserved Domains (1) summary
      PRK13357
      Location:51 → 398
      PRK13357; branched-chain amino acid aminotransferase; Provisional

    3. XM_042245233.2 → XP_042101167.1  branched-chain-amino-acid aminotransferase, cytosolic isoform X2

      Related
      ENSOARP00020006071.2, ENSOART00020007341.2
      Conserved Domains (1) summary
      PRK13357
      Location:45 → 392
      PRK13357; branched-chain amino acid aminotransferase; Provisional
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9GKM4.1 GenPept UniProtKB/Swiss-Prot:Q9GKM4

    Gene LinkOut

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    Research Materials