PROP1 PROP paired-like homeobox 1 [Ovis aries (sheep)] - Gene

Summary

Gene symbol: PROP1
Gene description: PROP paired-like homeobox 1
See related: EnsemblRapid:ENSOARG00020015839
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Ovis aries
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	ARS-UI_Ramb_v3.0 (GCF_016772045.2)	5	NC_056058.1 (37525267..37528053)

Chromosome 5 - NC_056058.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_056058.1 Chromosome 5 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Study confirms the role of PROP1 polymorphisms on growth traits in sheep.
Title: Gene polymorphisms in PROP1 associated with growth traits in sheep.
This study reports the polymorphism of Prophet of Pit-1 gene and its relationship with litter size of Small Tail Han sheep.
Title: Polymorphism of Prophet of Pit-1 gene and its relationship with litter size of Small Tail Han sheep.
PROP1 protein, encoded by two alleles, is associated with the nuclear matrix.
Title: Conserved amino acid sequences confer nuclear localization upon the Prophet of Pit-1 pituitary transcription factor protein.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in pituitary gland development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of transcription regulator complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: homeobox protein prophet of Pit-1

Names: prophet of POU1F1; prophet of Pit-1; prophet of Pit1, paired-like homeodomain transcription factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.