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    AQP3 aquaporin 3 (Gill blood group) [ Ovis aries (sheep) ]

    Gene ID: 443047, updated on 5-Mar-2024

    Summary

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    Gene symbol
    AQP3
    Gene description
    aquaporin 3 (Gill blood group)
    See related
    EnsemblRapid:ENSOARG00020009201
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    See AQP3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 2 NC_056055.1 (37724693..37730555)

    Chromosome 2 - NC_056055.1Genomic Context describing neighboring genes Neighboring gene ubiquitin conjugating enzyme E2 R2 Neighboring gene nucleolar protein 6 Neighboring gene aquaporin 7 Neighboring gene nuclear transcription factor, X-box binding 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056055.1 Chromosome 2 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ontogeny of aquaporins 1 and 3 in ovine placenta and fetal membranes. Johnston H, et al. Placenta, 2000 Jan. PMID 10692256
    2. Modulation of aquaporins 3 and 9 after exposure of ovine ovarian tissue to cryoprotectants followed by in vitro culture. Sales AD, et al. Cell Tissue Res, 2016 Aug. PMID 26975215
    3. Immunolocalization of aquaporins 1, 3, and 5 in the nasal respiratory mucosa of a panting species, the sheep (Ovis aries). Vesterdorf K, et al. J Therm Biol, 2014 Jul. PMID 24956959
    4. Quantitative comparison of placental expression of three aquaporin genes. Liu H, et al. Placenta, 2004 Jul. PMID 15135229
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AQP3 and AQP9 act in a mutually dependent way, maintaining the cell homeostasis that is essential for the ovary cryopreservation process.
      Title: Modulation of aquaporins 3 and 9 after exposure of ovine ovarian tissue to cryoprotectants followed by in vitro culture.
    2. AQP1, 3, and 5 may constitute a transepithelial water pathway via glandular secretions and across the surface epithelium, which provides a possible means for rapid and controllable water movement in the nasal respiratory mucosa of a panting species
      Title: Immunolocalization of aquaporins 1, 3, and 5 in the nasal respiratory mucosa of a panting species, the sheep (Ovis aries).
    3. expression of aquaporins 1, 3, and 8 underlie the high water and urea permeability of the ovine placenta in the last half of pregnancy
      Title: Quantitative comparison of placental expression of three aquaporin genes.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glycerol channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables urea transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables water channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycerol transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in water transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basolateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    aquaporin-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056055.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      37724693..37730555
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027964294.2 → XP_027820095.1  aquaporin-3

      UniProtKB/TrEMBL
      A0A836AL46
      Related
      ENSOARP00020011652.1, ENSOART00020014124.2
    Nucleotide Protein Strain
    Heading Accession and Version

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