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    HMGA1 high mobility group AT-hook 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 442946, updated on 5-Mar-2024

    Summary

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    Official Symbol
    HMGA1provided by VGNC
    Official Full Name
    high mobility group AT-hook 1provided by VGNC
    Primary source
    VGNC:VGNC:41709
    See related
    Ensembl:ENSCAFG00845026595
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    HMGIY; HMGA1A
    Orthologs
    human mouse all
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    Genomic context

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    See HMGA1 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (3865251..3874712)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (3544725..3554094)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (3707513..3716880)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (3527697..3537024)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (3609068..3618412)

    Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106559595 Neighboring gene glutamate metabotropic receptor 4 Neighboring gene U6 spliceosomal RNA Neighboring gene small integral membrane protein 29

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic characterisation, chromosomal assignment and in vivo localisation of the canine high mobility group A1 (HMGA1) gene. Beuing C, et al. BMC Genet, 2008 Jul 23. PMID 18651940, Free PMC Article
    2. Expression of the high mobility group A1 (HMGA1) and A2 (HMGA2) genes in canine lymphoma: analysis of 23 cases and comparison to control cases. Joetzke AE, et al. Vet Comp Oncol, 2010 Jun. PMID 20579321
    3. The canine HMGA1. Murua Escobar H, et al. Gene, 2004 Apr 14. PMID 15087128

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. expressed significantly higher in dogs with lymphoma compared to control cases
      Title: Expression of the high mobility group A1 (HMGA1) and A2 (HMGA2) genes in canine lymphoma: analysis of 23 cases and comparison to control cases.
    2. HMGA1 gene has been assigned to canine chromosome 12q11, and consists of of 7 exons and 6 introns spanning in total 9524 bp.
      Title: Genomic characterisation, chromosomal assignment and in vivo localisation of the canine high mobility group A1 (HMGA1) gene.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    high mobility group protein HMG-I/HMG-Y
    Names
    HMG-I(Y)
    high mobility group AT-hook protein 1
    high mobility group HMGA1A
    high mobility group HMGA1B
    high mobility group protein 1A
    high mobility group protein A1
    non-histone protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003387.1 → NP_001003387.1  high mobility group protein HMG-I/HMG-Y

      See identical proteins and their annotated locations for NP_001003387.1

      Status: PROVISIONAL

      Source sequence(s)
      AY366390
      UniProtKB/Swiss-Prot
      Q6URC2
      UniProtKB/TrEMBL
      A0A8C0K0G1, Q2TUW3

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051816.1 Reference ROS_Cfam_1.0

      Range
      3865251..3874712
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038682696.1 → XP_038538624.1  high mobility group protein HMG-I/HMG-Y isoform X1

      UniProtKB/TrEMBL
      Q6UQF0, Q6UQF9
      Related
      ENSCAFP00845036824.1, ENSCAFT00845046941.1

    2. XM_038682697.1 → XP_038538625.1  high mobility group protein HMG-I/HMG-Y isoform X2

      UniProtKB/Swiss-Prot
      Q6URC2
      UniProtKB/TrEMBL
      A0A8C0K0G1, Q2TUW3

    3. XM_038682695.1 → XP_038538623.1  high mobility group protein HMG-I/HMG-Y isoform X1

      UniProtKB/TrEMBL
      Q6UQF0, Q6UQF9

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049272.1 Alternate UMICH_Zoey_3.1

      Range
      3527697..3537024
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

      Range
      3609068..3618412
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

      Range
      3707513..3716880
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      3544725..3554094
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6URC2.3 GenPept UniProtKB/Swiss-Prot:Q6URC2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.