mrpl46 mitochondrial ribosomal protein L46 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mrpl46provided by ZNC
Official Full Name: mitochondrial ribosomal protein L46provided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-224
See related: Ensembl:ENSDARG00000016307 AllianceGenome:ZFIN:ZDB-GENE-040718-224
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fk88g07; zgc:92810; wu:fk88g07
Summary: Predicted to be a structural constituent of ribosome. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL46 (mitochondrial ribosomal protein L46). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (14536107..14543256)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (14290644..14297793)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of mitochondrial large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: large ribosomal subunit protein mL46

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002518.1 → NP_001002518.1 large ribosomal subunit protein mL46

See identical proteins and their annotated locations for NP_001002518.1

Status: PROVISIONAL

Source sequence(s)

BC076280

UniProtKB/TrEMBL

Q6DGR0

Related

ENSDARP00000007227.7, ENSDART00000027331.10

Conserved Domains (2) summary

cd04661
Location:152 → 282

MRP_L46; Mitochondrial ribosomal protein L46 (MRP L46) is a component of the large subunit (39S) of the mammalian mitochondrial ribosome and a member of the Nudix hydrolase superfamily. MRPs are thought to be involved in the maintenance of the mitochondrial DNA. ...

pfam11788
Location:49 → 144

MRP-L46; 39S mitochondrial ribosomal protein L46