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    GRM8 glutamate metabotropic receptor 8 [ Gallus gallus (chicken) ]

    Gene ID: 427853, updated on 17-Aug-2024

    Summary

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    Symbol
    GRM8provided by CGNC
    Full Name
    glutamate metabotropic receptor 8provided by CGNC
    Primary source
    CGNC:13848
    See related
    Ensembl:ENSGALG00010001223
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See GRM8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (21099878..21424088)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (21332150..21677564)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene plexin B2 Neighboring gene uncharacterized LOC121110877 Neighboring gene uncharacterized LOC121109516 Neighboring gene translation initiation factor IF-2-like Neighboring gene zinc finger protein 800 Neighboring gene protection of telomeres 1 Neighboring gene G protein-coupled receptor 37

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables group III metabotropic glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled glutamate receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    metabotropic glutamate receptor 8
    Names
    glutamate receptor, metabotropic 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      21099878..21424088
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_425426.8 → XP_425426.3  metabotropic glutamate receptor 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XA35
      Related
      ENSGALP00010001379.1, ENSGALT00010002829.1
      Conserved Domains (3) summary
      cd15454
      Location:582 → 892
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06376
      Location:40 → 504
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:512 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. XM_046903818.1 → XP_046759774.1  metabotropic glutamate receptor 8 isoform X2

    3. XM_046903819.1 → XP_046759775.1  metabotropic glutamate receptor 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XA35

    4. XM_040652895.2 → XP_040508829.1  metabotropic glutamate receptor 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XA35
      Conserved Domains (3) summary
      cd15454
      Location:582 → 892
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06376
      Location:40 → 504
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:512 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    5. XM_040652898.2 → XP_040508832.1  metabotropic glutamate receptor 8 isoform X3

      Conserved Domains (2) summary
      cd15454
      Location:303 → 613
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cl10011
      Location:1 → 225
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      21332150..21677564
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040659542.2 → XP_040515476.1  metabotropic glutamate receptor 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XA35
      Conserved Domains (3) summary
      cd15454
      Location:582 → 892
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06376
      Location:40 → 504
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:512 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. XM_040659547.2 → XP_040515481.1  metabotropic glutamate receptor 8 isoform X5

      Conserved Domains (3) summary
      cd06376
      Location:40 → 499
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      cd14964
      Location:500 → 525
      7tm_GPCRs; TM helix 7 [structural motif]
      cl28897
      Location:492 → 594
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    3. XM_046909352.1 → XP_046765308.1  metabotropic glutamate receptor 8 isoform X2

    4. XM_046909353.1 → XP_046765309.1  metabotropic glutamate receptor 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XA35

    5. XM_040659543.2 → XP_040515477.1  metabotropic glutamate receptor 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XA35
      Conserved Domains (3) summary
      cd15454
      Location:582 → 892
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06376
      Location:40 → 504
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:512 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    6. XM_040659546.2 → XP_040515480.1  metabotropic glutamate receptor 8 isoform X3

      Conserved Domains (2) summary
      cd15454
      Location:303 → 613
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cl10011
      Location:1 → 225
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    7. XM_040659544.1 → XP_040515478.1  metabotropic glutamate receptor 8 isoform X4

      Conserved Domains (2) summary
      cd15454
      Location:350 → 660
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cl10011
      Location:11 → 272
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
    Nucleotide Protein
    Heading Accession and Version

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