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    ASB12 ankyrin repeat and SOCS box containing 12 [ Gallus gallus (chicken) ]

    Gene ID: 422313, updated on 17-Aug-2024

    Summary

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    Symbol
    ASB12provided by CGNC
    Full Name
    ankyrin repeat and SOCS box containing 12provided by CGNC
    Primary source
    CGNC:5730
    See related
    Ensembl:ENSGALG00010013382
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See ASB12 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (11613621..11618190)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (11647180..11651743)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene chromosome 8 open reading frame 48 Neighboring gene uncharacterized LOC101750229 Neighboring gene microRNA 1790 Neighboring gene myotubularin related protein 8 Neighboring gene APC membrane recruitment protein 1 Neighboring gene Cdc42 guanine nucleotide exchange factor 9 Neighboring gene uncharacterized LOC124417921

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of barbed-end actin filament capping IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ankyrin repeat and SOCS box protein 12
    Names
    ankyrin repeat and SOCS box-containing protein 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001277670.1 → NP_001264599.1  ankyrin repeat and SOCS box protein 12

      Status: VALIDATED

      Source sequence(s)
      BU260206, CR354354
      Conserved Domains (5) summary
      cd00204
      Location:74 → 200
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam07525
      Location:274 → 312
      SOCS_box; SOCS box
      pfam12796
      Location:76 → 167
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:140 → 200
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:74 → 102
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      11613621..11618190
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040698846.2 → XP_040554780.1  ankyrin repeat and SOCS box protein 12 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YK92
      Related
      ENSGALP00010019003.1, ENSGALT00010032213.1
      Conserved Domains (3) summary
      sd00045
      Location:86 → 114
      ANK; ANK repeat [structural motif]
      cl02533
      Location:286 → 326
      SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...
      cl39094
      Location:85 → 252
      Ank_2; Ankyrin repeats (3 copies)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      11647180..11651743
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046915837.1 → XP_046771793.1  ankyrin repeat and SOCS box protein 12 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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