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    AKT3 AKT serine/threonine kinase 3 [ Gallus gallus (chicken) ]

    Gene ID: 421497, updated on 10-Oct-2024

    Summary

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    Symbol
    AKT3provided by CGNC
    Full Name
    AKT serine/threonine kinase 3provided by CGNC
    Primary source
    CGNC:8138
    See related
    Ensembl:ENSGALG00010008323
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See AKT3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (34651696..34796287)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (34565715..34710127)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110494 Neighboring gene zinc finger and BTB domain containing 18 Neighboring gene uncharacterized LOC124418350 Neighboring gene serologically defined colon cancer antigen 8 Neighboring gene uncharacterized LOC121113143 Neighboring gene centrosomal protein 170

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of AKT/PKB signaling in fibroblast growth factor-1 (FGF-1)-induced angiogenesis in the chicken chorioallantoic membrane (CAM). Forough R, et al. J Cell Biochem, 2005 Jan 1. PMID 15517595
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PKB/AKT signaling plays a role in FGF-1-stimulated angiogenesis in vivo and the AKT pathway may serve as a therapeutic target for angiogenesis-associated diseases
      Title: Role of AKT/PKB signaling in fibroblast growth factor-1 (FGF-1)-induced angiogenesis in the chicken chorioallantoic membrane (CAM).
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RAC-gamma serine/threonine-protein kinase
    Names
    v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
    XP_015139467.1
    XP_040522465.1
    XP_040522466.1
    XP_040553345.1
    XP_046770379.1
    XP_046770380.1
    XP_046795335.1
    XP_046795336.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      34651696..34796287
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015283981.4 → XP_015139467.1  RAC-gamma serine/threonine-protein kinase isoform X1

      UniProtKB/TrEMBL
      A0A1D5NTY9, A0A1L1RUI3, A0A8V0XTB6
      Conserved Domains (2) summary
      cd01241
      Location:4 → 110
      PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
      cd05593
      Location:132 → 479
      STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

    2. XM_040697411.2 → XP_040553345.1  RAC-gamma serine/threonine-protein kinase isoform X1

      UniProtKB/TrEMBL
      A0A1D5NTY9, A0A1L1RUI3, A0A8V0XTB6
      Related
      ENSGALP00010011460.1, ENSGALT00010019912.1
      Conserved Domains (2) summary
      cd01241
      Location:4 → 110
      PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
      cd05593
      Location:132 → 479
      STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

    3. XM_046939380.1 → XP_046795336.1  RAC-gamma serine/threonine-protein kinase isoform X2

    4. XM_046939379.1 → XP_046795335.1  RAC-gamma serine/threonine-protein kinase isoform X1

      UniProtKB/TrEMBL
      A0A1D5NTY9, A0A1L1RUI3

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      34565715..34710127
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040666532.2 → XP_040522466.1  RAC-gamma serine/threonine-protein kinase isoform X1

      UniProtKB/TrEMBL
      A0A1D5NTY9, A0A1L1RUI3, A0A8V0XTB6
      Conserved Domains (2) summary
      cd01241
      Location:4 → 110
      PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
      cd05593
      Location:132 → 479
      STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

    2. XM_040666531.2 → XP_040522465.1  RAC-gamma serine/threonine-protein kinase isoform X1

      UniProtKB/TrEMBL
      A0A1D5NTY9, A0A1L1RUI3, A0A8V0XTB6
      Conserved Domains (2) summary
      cd01241
      Location:4 → 110
      PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
      cd05593
      Location:132 → 479
      STKc_PKB_gamma; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B gamma (also called Akt3)

    3. XM_046914424.1 → XP_046770380.1  RAC-gamma serine/threonine-protein kinase isoform X2

    4. XM_046914423.1 → XP_046770379.1  RAC-gamma serine/threonine-protein kinase isoform X1

      UniProtKB/TrEMBL
      A0A1D5NTY9, A0A1L1RUI3
    Nucleotide Protein Strain
    Heading Accession and Version

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