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    NAMPTP1 nicotinamide phosphoribosyltransferase pseudogene 1 [ Gallus gallus (chicken) ]

    Gene ID: 417707, updated on 10-Oct-2024

    Summary

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    Symbol
    NAMPTP1provided by CGNC
    Full Name
    nicotinamide phosphoribosyltransferase pseudogene 1provided by CGNC
    Primary source
    CGNC:50574
    See related
    Ensembl:ENSGALG00010010351
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    NAMPT; PBEF1; visfatin
    Orthologs
    human mouse all
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    Genomic context

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    See NAMPTP1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (14422059..14450332, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (14559847..14588245, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107051630 Neighboring gene synaptophysin like 1 Neighboring gene uncharacterized LOC121108728 Neighboring gene uncharacterized LOC107051631

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression and effect of NAMPT (visfatin) on progesterone secretion in hen granulosa cells. Diot M, et al. Reproduction, 2015 Jul. PMID 25918435
    2. Novel 9-bp indel in visfatin gene and its associations with chicken growth. Han RL, et al. Br Poult Sci, 2011 Feb. PMID 21337198
    3. A novel single-nucleotide polymorphism of the visfatin gene and its associations with performance traits in the chicken. Han RL, et al. J Appl Genet, 2010. PMID 20145301
    4. Visfatin gene expression in chickens is sex and tissue dependent. Ons E, et al. Domest Anim Endocrinol, 2010 Feb. PMID 19786337
    5. NAMPT (visfatin) in the chicken testis: influence of sexual maturation on cellular localization, plasma levels and gene and protein expression. Ocón-Grove OM, et al. Reproduction, 2010 Jan. PMID 19736255

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. NAMPT is present in hen ovarian cells and inhibits progesterone production in granulosa cells.
      Title: Expression and effect of NAMPT (visfatin) on progesterone secretion in hen granulosa cells.
    2. The cloned 1,372-bp fragment upstream of the putative translation start site (ATG) displayed the maximal promoter activity in cultured cells. Visfatin gene transcription was likely controlled by multiple promoters near the translation start site.
      Title: Characterization of chicken visfatin gene: cDNA cloning, tissue distribution, and promoter analysis.
    3. Nampt/visfatin/PBEF affects expression of myogenic regulatory factors and is regulated by interleukin-6 in chicken skeletal muscle cells
      Title: Nampt/visfatin/PBEF affects expression of myogenic regulatory factors and is regulated by interleukin-6 in chicken skeletal muscle cells.
    4. A indel mutation within the visfatin gene is negatively associated with skeletal growth.
      Title: Novel 9-bp indel in visfatin gene and its associations with chicken growth.
    5. Single-nucleotide polymorphism of the visfatin gene is associated with performance traits
      Title: A novel single-nucleotide polymorphism of the visfatin gene and its associations with performance traits in the chicken.
    6. results showed that the visfatin gene is expressed in chickens with greater abundance in muscle, and that it is regulated in a tissue-specific manner by energy balance-related factors
      Title: Visfatin gene expression in chickens is sex and tissue dependent.
    7. sexual maturation is associated with several changes in testicular NAMPT expression indicating that NAMPT is likely to play a significant role in testicular functions such as spermatogenesis and steroidogenesis
      Title: NAMPT (visfatin) in the chicken testis: influence of sexual maturation on cellular localization, plasma levels and gene and protein expression.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nicotinamide phosphoribosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in NAD biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nicotinamide phosphoribosyltransferase
    Names
    pre-B-cell colony-enhancing factor 1
    NP_001025899.1
    XP_015131202.1
    XP_046763010.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030728.2 → NP_001025899.1  nicotinamide phosphoribosyltransferase

      See identical proteins and their annotated locations for NP_001025899.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      A0A8V0YDK3, Q58I02
      Related
      ENSGALP00010014045.1, ENSGALT00010024772.1
      Conserved Domains (1) summary
      cd01569
      Location:13 → 429
      PBEF_like; pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general, ...

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      14422059..14450332 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015275716.4 → XP_015131202.1  nicotinamide phosphoribosyltransferase isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y502, A0A8V0YDK3
      Related
      ENSGALP00010014035.1, ENSGALT00010024749.1
      Conserved Domains (2) summary
      PRK09198
      Location:11 → 491
      PRK09198; putative nicotinate phosphoribosyltransferase; Provisional
      cd01569
      Location:13 → 435
      PBEF_like; pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general, ...

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      14559847..14588245 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046907054.1 → XP_046763010.1  nicotinamide phosphoribosyltransferase isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y502
    Nucleotide Protein Strain
    Heading Accession and Version

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