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    LINGO1 leucine rich repeat and Ig domain containing 1 [ Gallus gallus (chicken) ]

    Gene ID: 415344, updated on 17-Aug-2024

    Summary

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    Symbol
    LINGO1provided by CGNC
    Full Name
    leucine rich repeat and Ig domain containing 1provided by CGNC
    Primary source
    CGNC:1953
    See related
    Ensembl:ENSGALG00010020771
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    LRRN6A; LINGO-1
    Orthologs
    human mouse all
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    Genomic context

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    See LINGO1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (2763080..2863017)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (2635694..2735812)

    Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene sorting nexin 33 Neighboring gene chondroitin sulfate proteoglycan 4 Neighboring gene high mobility group 20A Neighboring gene pseudopodium enriched atypical kinase 1 Neighboring gene uncharacterized LOC121111653 Neighboring gene tetraspanin 3 Neighboring gene proline-serine-threonine phosphatase interacting protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression pattern of LINGO-1 in the developing nervous system of the chick embryo. Okafuji T, et al. Gene Expr Patterns, 2005 Dec. PMID 16024296
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The expression of cLINGO-1 in the developing brain and spinal cord of the chick embryo was examined.
      Title: Expression pattern of LINGO-1 in the developing nervous system of the chick embryo.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
    Names
    cLINGO-1
    leucine rich repeat neuronal 6A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024577.2 → NP_001019748.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 precursor

      See identical proteins and their annotated locations for NP_001019748.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000245
      UniProtKB/Swiss-Prot
      Q50L44
      Related
      ENSGALP00010029694.1, ENSGALT00010050243.1
      Conserved Domains (5) summary
      TIGR00864
      Location:334 → 414
      PCC; polycystin cation channel protein
      sd00033
      Location:90 → 113
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:113 → 172
      LRR_8; Leucine rich repeat
      cd20969
      Location:416 → 507
      IgI_Lingo-1; Immunoglobulin I-set domain of the Leucine-rich repeat and immunoglobin-like domain-containing protein 1 (Lingo-1)
      cd21340
      Location:183 → 364
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      2763080..2863017
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046898994.1 → XP_046754950.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44
      Related
      ENSGALP00010029692.1, ENSGALT00010050239.1

    2. XM_046898996.1 → XP_046754952.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44
      Related
      ENSGALP00010029696.1, ENSGALT00010050246.1

    3. XM_046898999.1 → XP_046754955.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44
      Related
      ENSGALP00010029680.1, ENSGALT00010050223.1

    4. XM_046898995.1 → XP_046754951.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    5. XM_046898998.1 → XP_046754954.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    6. XM_046899001.1 → XP_046754957.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    7. XM_046898997.1 → XP_046754953.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    8. XM_040706284.2 → XP_040562218.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44
      Conserved Domains (5) summary
      TIGR00864
      Location:334 → 414
      PCC; polycystin cation channel protein
      sd00033
      Location:90 → 113
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:113 → 172
      LRR_8; Leucine rich repeat
      cd20969
      Location:416 → 507
      IgI_Lingo-1; Immunoglobulin I-set domain of the Leucine-rich repeat and immunoglobin-like domain-containing protein 1 (Lingo-1)
      cd21340
      Location:183 → 364
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    9. XM_046899000.1 → XP_046754956.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    10. XM_046899002.1 → XP_046754958.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44
      Related
      ENSGALP00010029682.1, ENSGALT00010050225.1

    11. XM_040706282.2 → XP_040562216.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X1

      UniProtKB/TrEMBL
      A9DA44
      Conserved Domains (5) summary
      TIGR00864
      Location:340 → 420
      PCC; polycystin cation channel protein
      sd00033
      Location:96 → 119
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:119 → 178
      LRR_8; Leucine rich repeat
      cd20969
      Location:422 → 513
      IgI_Lingo-1; Immunoglobulin I-set domain of the Leucine-rich repeat and immunoglobin-like domain-containing protein 1 (Lingo-1)
      cd21340
      Location:189 → 370
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    12. XM_040706283.2 → XP_040562217.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X2

      UniProtKB/TrEMBL
      A9DA44
      Conserved Domains (5) summary
      TIGR00864
      Location:340 → 420
      PCC; polycystin cation channel protein
      sd00033
      Location:96 → 119
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:119 → 178
      LRR_8; Leucine rich repeat
      cd20969
      Location:422 → 513
      IgI_Lingo-1; Immunoglobulin I-set domain of the Leucine-rich repeat and immunoglobin-like domain-containing protein 1 (Lingo-1)
      cd21340
      Location:189 → 370
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      2635694..2735812
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046924734.1 → XP_046780690.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    2. XM_046924736.1 → XP_046780692.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    3. XM_046924739.1 → XP_046780695.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    4. XM_046924735.1 → XP_046780691.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    5. XM_046924738.1 → XP_046780694.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    6. XM_046924741.1 → XP_046780697.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    7. XM_046924737.1 → XP_046780693.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    8. XM_046924733.1 → XP_046780689.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    9. XM_046924740.1 → XP_046780696.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    10. XM_046924742.1 → XP_046780698.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q50L44

    11. XM_046924731.1 → XP_046780687.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X1

      UniProtKB/TrEMBL
      A9DA44

    12. XM_046924732.1 → XP_046780688.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X2

      UniProtKB/TrEMBL
      A9DA44
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q50L44.1 GenPept UniProtKB/Swiss-Prot:Q50L44

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