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    dpr15 defective proboscis extension response 15 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41473, updated on 18-Sep-2024

    Summary

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    Official Symbol
    dpr15provided by FlyBase
    Official Full Name
    defective proboscis extension response 15provided by FlyBase
    Primary source
    FLYBASE:FBgn0037993
    Locus tag
    Dmel_CG10095
    See related
    AllianceGenome:FB:FBgn0037993
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10095; CT28423; Dmel\CG10095; Dpr-15; Dpr15
    Summary
    Involved in synapse organization. Predicted to be active in neuron projection membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See dpr15 in Genome Data Viewer
    Location:
    87A10-87B1; 3-52 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12138833..12158595, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7964555..7984317, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene transfer RNA:Lysine-TTT 2-5 Neighboring gene uncharacterized protein Neighboring gene Calphotin Neighboring gene eukaryotic translation initiation factor 3 subunit d2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A global timing mechanism regulates cell-type-specific wiring programmes. Jain S, et al. Nature, 2022 Mar. PMID 35197627
    2. Combinations of DIPs and Dprs control organization of olfactory receptor neuron terminals in Drosophila. Barish S, et al. PLoS Genet, 2018 Aug. PMID 30102700, Free PMC Article
    3. Defective proboscis extension response (DPR), a member of the Ig superfamily required for the gustatory response to salt. Nakamura M, et al. J Neurosci, 2002 May 1. PMID 11978823, Free PMC Article
    4. Neural immunoglobulin superfamily interaction networks. Zinn K, et al. Curr Opin Neurobiol, 2017 Aug. PMID 28558267, Free PMC Article
    5. Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons. Wang Y, et al. Development, 2022 May 15. PMID 35502740, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synapse organization IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in neuron projection membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    defective proboscis extension response 15
    Names
    CG10095-PA
    CG10095-PB
    dpr15-PA
    dpr15-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12138833..12158595 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300370.1 → NP_001287299.1  defective proboscis extension response 15, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287299.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MQZ9, Q9VGD0
      Conserved Domains (2) summary
      smart00410
      Location:197 → 289
      IG_like; Immunoglobulin like
      pfam07686
      Location:204 → 290
      V-set; Immunoglobulin V-set domain

    2. NM_169453.1 → NP_731672.1  defective proboscis extension response 15, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731672.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MQZ9, Q9VGD0
      Related
      FBpp0082022, FBtr0082549
      Conserved Domains (2) summary
      smart00410
      Location:197 → 289
      IG_like; Immunoglobulin like
      pfam07686
      Location:204 → 290
      V-set; Immunoglobulin V-set domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MQZ9 Q8MQZ9
    Q9VGD0 Q9VGD0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
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