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    EPHX2 epoxide hydrolase 2 [ Sus scrofa (pig) ]

    Gene ID: 414425, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EPHX2provided by VGNC
    Official Full Name
    epoxide hydrolase 2provided by VGNC
    Primary source
    VGNC:VGNC:107387
    See related
    Ensembl:ENSSSCG00000009666
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Broad expression in kidney (RPKM 122.7), liver (RPKM 82.0) and 6 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See EPHX2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 14 NC_010456.5 (11217125..11293018)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 14 NC_010456.4 (12397646..12473595)

    Chromosome 14 - NC_010456.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110256728 Neighboring gene tripartite motif containing 35 Neighboring gene protein tyrosine kinase 2 beta Neighboring gene cholinergic receptor nicotinic alpha 2 subunit Neighboring gene gulonolactone (L-) oxidase Neighboring gene clusterin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Cytochrome p450-dependent lipid metabolism in preovulatory follicles. Newman JW, et al. Endocrinology, 2004 Nov. PMID 15308618
    2. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890, Free PMC Article
    3. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    4. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables lipid phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phospholipid dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bifunctional epoxide hydrolase 2
    Names
    CEH
    SEH
    cytosolic epoxide hydrolase
    epoxide hydratase
    soluble epoxide hydrolase
    NP_001001641.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001641.1 → NP_001001641.1  bifunctional epoxide hydrolase 2

      See identical proteins and their annotated locations for NP_001001641.1

      Status: PROVISIONAL

      Source sequence(s)
      AY566232
      UniProtKB/Swiss-Prot
      Q6Q2C2
      UniProtKB/TrEMBL
      A0A8D1NFN2
      Related
      ENSSSCP00000010323.3, ENSSSCT00000010599.5
      Conserved Domains (4) summary
      TIGR02247
      Location:2 → 219
      HAD-1A3-hyp; epoxide hydrolase N-terminal domain-like phosphatase
      pfam00561
      Location:259 → 531
      Abhydrolase_1; alpha/beta hydrolase fold
      cl21460
      Location:5 → 197
      HAD_like; Haloacid Dehalogenase-like Hydrolases
      cl21494
      Location:241 → 542
      Abhydrolase; alpha/beta hydrolases

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010456.5 Reference Sscrofa11.1 Primary Assembly

      Range
      11217125..11293018
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6Q2C2.1 GenPept UniProtKB/Swiss-Prot:Q6Q2C2

    Gene LinkOut

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