HEY1 hes related family bHLH transcription factor with YRPW motif 1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: HEY1provided by VGNC
Official Full Name: hes related family bHLH transcription factor with YRPW motif 1provided by VGNC
Primary source: VGNC:VGNC:29828
See related: BGD:BT19460; Ensembl:ENSBTAG00000015717
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: CHF2
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	14	NC_037341.1 (42969171..42972066, complement)

Chromosome 14 - NC_037341.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Notch signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in anterior/posterior pattern specification	IEA Inferred from Electronic Annotation more info	PubMed
involved_in circulatory system development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of neuron differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of neurogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: hairy/enhancer-of-split related with YRPW motif protein 1

Names: cardiovascular basic helix-loop-helix factor 2; hairy/enhancer-of-split related with YRPW motif 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001001172.3 → NP_001001172.2 hairy/enhancer-of-split related with YRPW motif protein 1

See identical proteins and their annotated locations for NP_001001172.2

Status: PROVISIONAL

Source sequence(s)

BC112574

UniProtKB/Swiss-Prot

Q2KIN4

UniProtKB/TrEMBL

Q760I8

Related

ENSBTAP00000020864.4, ENSBTAT00000020864.5

Conserved Domains (2) summary

smart00511
Location:120 → 166

ORANGE; Orange domain

cd00083
Location:50 → 107

HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...