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    VCAM1 vascular cell adhesion molecule 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 403982, updated on 17-Aug-2024

    Summary

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    Official Symbol
    VCAM1provided by VGNC
    Official Full Name
    vascular cell adhesion molecule 1provided by VGNC
    Primary source
    VGNC:VGNC:48240
    See related
    Ensembl:ENSCAFG00845012277
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See VCAM1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (49686812..49704968, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (52013558..52031171, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (49789615..49807229, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (49380130..49397749, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (49359940..49377559, complement)

    Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111096514 Neighboring gene uncharacterized LOC119872253 Neighboring gene uncharacterized LOC119881528 Neighboring gene G protein-coupled receptor 88

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vascular cell adhesion protein 1
    Names
    V-CAM 1
    VCAM-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003298.1 → NP_001003298.1  vascular cell adhesion protein 1 precursor

      See identical proteins and their annotated locations for NP_001003298.1

      Status: PROVISIONAL

      Source sequence(s)
      U32086
      UniProtKB/Swiss-Prot
      Q28260
      UniProtKB/TrEMBL
      A0A8C0PVW3, A0A8C0QZC8, A0A8I3NNW2
      Related
      ENSCAFP00845017196.1, ENSCAFT00845021861.1
      Conserved Domains (7) summary
      cd07689
      Location:404 → 502
      Ig2_VCAM-1; Second immunoglobulin (Ig)-like domain of vascular endothelial cell adhesion molecule-1 (VCAM-1, CD106) and intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins
      smart00408
      Location:238 → 298
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:232 → 308
      IG_like; Immunoglobulin like
      pfam07679
      Location:26 → 112
      I-set; Immunoglobulin I-set domain
      pfam00047
      Location:318 → 385
      ig; Immunoglobulin domain
      pfam13927
      Location:606 → 672
      Ig_3; Immunoglobulin domain
      cl11960
      Location:30 → 98
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051810.1 Reference ROS_Cfam_1.0

      Range
      49686812..49704968 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038667558.1 → XP_038523486.1  vascular cell adhesion protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PVW3, A0A8C0QZC8, A0A8I3NNW2
      Conserved Domains (5) summary
      smart00408
      Location:247 → 307
      IGc2; Immunoglobulin C-2 Type
      smart00409
      Location:528 → 605
      IG; Immunoglobulin
      cd00096
      Location:322 → 327
      Ig; Ig strand A [structural motif]
      cd07689
      Location:413 → 513
      IgC2_VCAM-1; Immunoglobulin (Ig)-like domain of vascular endothelial cell adhesion molecule-1 (VCAM-1) and similar proteins; member of the C2-set of IgSF domains
      cl11960
      Location:322 → 410
      Ig; Immunoglobulin domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049266.1 Alternate UMICH_Zoey_3.1

      Range
      49380130..49397749 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

      Range
      49359940..49377559 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

      Range
      49789615..49807229 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      52013558..52031171 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q28260.1 GenPept UniProtKB/Swiss-Prot:Q28260

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials