ME1 malic enzyme 1 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: ME1provided by VGNC
Official Full Name: malic enzyme 1provided by VGNC
Primary source: VGNC:VGNC:43109
See related: Ensembl:ENSCAFG00845011557
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	12	NC_051816.1 (44390732..44586598, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	12	NC_006594.4 (43436816..43632406, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	12	NC_049233.1 (43840059..44036221, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	12	NC_049272.1 (43730159..43925658, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	12	NC_049753.1 (43679098..43858889, complement)

Chromosome 12 - NC_051816.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

ME1 (e-PCR)
- UniSTS:266164

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables NAD binding	IEA Inferred from Electronic Annotation more info	PubMed
enables malate dehydrogenase (decarboxylating) (NAD+) activity	IEA Inferred from Electronic Annotation more info	PubMed
enables malate dehydrogenase (decarboxylating) (NADP+) activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in malate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in pyruvate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: NADP-dependent malic enzyme

Names: malic enzyme 1, NADP(+)-dependent, cytosolic

XP_038348273.1

EC 1.1.1.4

EC 1.1.1.40

XP_038348274.1

EC 1.1.1.4

EC 1.1.1.40

XP_038348275.1

EC 1.1.1.4

EC 1.1.1.40

XP_038410559.1

EC 1.1.1.4

EC 1.1.1.40

XP_038410560.1

EC 1.1.1.4

EC 1.1.1.40

XP_038410561.1

EC 1.1.1.4

EC 1.1.1.40

XP_038474423.1

EC 1.1.1.4

EC 1.1.1.40

XP_038474425.1

EC 1.1.1.4

EC 1.1.1.40

XP_038527876.1

EC 1.1.1.4

EC 1.1.1.40

XP_038527893.1

EC 1.1.1.4

EC 1.1.1.40

XP_038539982.1

EC 1.1.1.4

EC 1.1.1.40

XP_038539984.1

EC 1.1.1.4

EC 1.1.1.40

XP_038539985.1

EC 1.1.1.4

EC 1.1.1.40

XP_532217.4

EC 1.1.1.4

EC 1.1.1.40

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051816.1 Reference ROS_Cfam_1.0

Range

44390732..44586598 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038684054.1 → XP_038539982.1 NADP-dependent malic enzyme isoform X2

UniProtKB/TrEMBL

A0A8C0MKN3, A0A8I3NIY1, A0A8I3NJ10, A0A8P0SP73

Related

ENSCAFP00845016069.1, ENSCAFT00845020496.1

Conserved Domains (1) summary

PLN03129
Location:14 → 551

PLN03129; NADP-dependent malic enzyme; Provisional
XM_038684057.1 → XP_038539985.1 NADP-dependent malic enzyme isoform X3

UniProtKB/TrEMBL

A0A8C0KSZ8

Related

ENSCAFP00845016155.1, ENSCAFT00845020597.1

Conserved Domains (1) summary

PLN03129
Location:1 → 476

PLN03129; NADP-dependent malic enzyme; Provisional
XM_038684056.1 → XP_038539984.1 NADP-dependent malic enzyme isoform X1

UniProtKB/TrEMBL

A0A8C0KSZ8, A0A8P0ST92

Conserved Domains (1) summary

PLN03129
Location:2 → 526

PLN03129; NADP-dependent malic enzyme; Provisional

Alternate UMICH_Zoey_3.1

Genomic

NC_049272.1 Alternate UMICH_Zoey_3.1

Range

43730159..43925658 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038492345.1 → XP_038348273.1 NADP-dependent malic enzyme isoform X2

Conserved Domains (1) summary

PLN03129
Location:14 → 551

PLN03129; NADP-dependent malic enzyme; Provisional
XM_038492347.1 → XP_038348275.1 NADP-dependent malic enzyme isoform X3

Conserved Domains (1) summary

PLN03129
Location:1 → 476

PLN03129; NADP-dependent malic enzyme; Provisional
XM_038492346.1 → XP_038348274.1 NADP-dependent malic enzyme isoform X1

Conserved Domains (1) summary

PLN03129
Location:2 → 526

PLN03129; NADP-dependent malic enzyme; Provisional

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049753.1 Alternate UNSW_CanFamBas_1.0

Range

43679098..43858889 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038618495.1 → XP_038474423.1 NADP-dependent malic enzyme isoform X2

Conserved Domains (1) summary

PLN03129
Location:14 → 551

PLN03129; NADP-dependent malic enzyme; Provisional
XM_038618497.1 → XP_038474425.1 NADP-dependent malic enzyme isoform X3

Conserved Domains (1) summary

PLN03129
Location:1 → 476

PLN03129; NADP-dependent malic enzyme; Provisional

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049233.1 Alternate UU_Cfam_GSD_1.0

Range

43840059..44036221 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038554631.1 → XP_038410559.1 NADP-dependent malic enzyme isoform X2

UniProtKB/TrEMBL

A0A8C0MKN3, A0A8I3NIY1, A0A8I3NJ10, A0A8P0SP73

Conserved Domains (1) summary

PLN03129
Location:14 → 551

PLN03129; NADP-dependent malic enzyme; Provisional
XM_038554633.1 → XP_038410561.1 NADP-dependent malic enzyme isoform X3

UniProtKB/TrEMBL

A0A8C0KSZ8

Conserved Domains (1) summary

PLN03129
Location:1 → 476

PLN03129; NADP-dependent malic enzyme; Provisional
XM_038554632.1 → XP_038410560.1 NADP-dependent malic enzyme isoform X1

UniProtKB/TrEMBL

A0A8C0KSZ8, A0A8P0ST92

Conserved Domains (1) summary

PLN03129
Location:2 → 526

PLN03129; NADP-dependent malic enzyme; Provisional

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

43436816..43632406 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038671948.1 → XP_038527876.1 NADP-dependent malic enzyme isoform X2

UniProtKB/TrEMBL

A0A8C0MKN3, A0A8I3NIY1, A0A8I3NJ10, A0A8P0SP73

Conserved Domains (1) summary

PLN03129
Location:14 → 551

PLN03129; NADP-dependent malic enzyme; Provisional
XM_038671965.1 → XP_038527893.1 NADP-dependent malic enzyme isoform X3

UniProtKB/TrEMBL

A0A8C0KSZ8

Conserved Domains (1) summary

PLN03129
Location:1 → 476

PLN03129; NADP-dependent malic enzyme; Provisional
XM_532217.6 → XP_532217.4 NADP-dependent malic enzyme isoform X1

UniProtKB/TrEMBL

A0A8C0KSZ8, A0A8P0ST92

Conserved Domains (1) summary

PLN03129
Location:2 → 526

PLN03129; NADP-dependent malic enzyme; Provisional