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    NPY1R neuropeptide Y receptor Y1 [ Canis lupus familiaris (dog) ]

    Gene ID: 399518, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NPY1Rprovided by VGNC
    Official Full Name
    neuropeptide Y receptor Y1provided by VGNC
    Primary source
    VGNC:VGNC:43937
    See related
    Ensembl:ENSCAFG00845006432
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See NPY1R in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (60338999..60348168, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (59946494..59947746, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (60034141..60035393, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (59574468..59575720, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (59665153..59666405, complement)

    Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111090126 Neighboring gene uncharacterized LOC111090127 Neighboring gene basic proline-rich protein-like Neighboring gene neuropeptide Y receptor Y5 Neighboring gene uncharacterized protein C3orf38-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Neuropeptide Y1 receptor vasoconstriction in exercising canine skeletal muscles. Buckwalter JB, et al. J Appl Physiol (1985), 2005 Dec. PMID 16099895
    2. Vasoconstriction in exercising skeletal muscles: a potential role for neuropeptide Y? Buckwalter JB, et al. Am J Physiol Heart Circ Physiol, 2004 Jul. PMID 15210450
    3. Characterization and molecular cloning of vascular neuropeptide Y receptor subtypes in pig and dog. Malmström RE, et al. Regul Pept, 1998 Sep 25. PMID 9802394
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These data support the hypothesis that NPY Y(1) receptors produce vasoconstriction in exercising skeletal muscle. [Neuropeptide Y1 receptor]
      Title: Neuropeptide Y1 receptor vasoconstriction in exercising canine skeletal muscles.
    2. data support the hypothesis that NPY Y(1) receptors can produce vasoconstriction in exercising skeletal muscle
      Title: Vasoconstriction in exercising skeletal muscles: a potential role for neuropeptide Y?
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables neuropeptide Y receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables neuropeptide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neuropeptide Y receptor type 1
    Names
    NPY1-R

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002930.1 → NP_001002930.1  neuropeptide Y receptor type 1

      See identical proteins and their annotated locations for NP_001002930.1

      Status: PROVISIONAL

      Source sequence(s)
      AF005778
      UniProtKB/Swiss-Prot
      O02813
      UniProtKB/TrEMBL
      A0A8C0JWJ0
      Conserved Domains (1) summary
      cd15395
      Location:40 → 330
      7tmA_NPY1R; neuropeptide Y receptor type 1, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051819.1 Reference ROS_Cfam_1.0

      Range
      60338999..60348168 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038687153.1 → XP_038543081.1  neuropeptide Y receptor type 1 isoform X1

      UniProtKB/Swiss-Prot
      O02813
      UniProtKB/TrEMBL
      A0A8C0JWJ0
      Related
      ENSCAFP00845008915.1, ENSCAFT00845011414.1
      Conserved Domains (1) summary
      cd15395
      Location:40 → 330
      7tmA_NPY1R; neuropeptide Y receptor type 1, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_038687156.1 → XP_038543084.1  neuropeptide Y receptor type 1 isoform X1

      UniProtKB/Swiss-Prot
      O02813
      UniProtKB/TrEMBL
      A0A8C0JWJ0
      Conserved Domains (1) summary
      cd15395
      Location:40 → 330
      7tmA_NPY1R; neuropeptide Y receptor type 1, member of the class A family of seven-transmembrane G protein-coupled receptors

    3. XM_038687159.1 → XP_038543087.1  neuropeptide Y receptor type 1 isoform X1

      UniProtKB/Swiss-Prot
      O02813
      UniProtKB/TrEMBL
      A0A8C0JWJ0
      Conserved Domains (1) summary
      cd15395
      Location:40 → 330
      7tmA_NPY1R; neuropeptide Y receptor type 1, member of the class A family of seven-transmembrane G protein-coupled receptors

    4. XM_038687155.1 → XP_038543083.1  neuropeptide Y receptor type 1 isoform X1

      UniProtKB/Swiss-Prot
      O02813
      UniProtKB/TrEMBL
      A0A8C0JWJ0
      Conserved Domains (1) summary
      cd15395
      Location:40 → 330
      7tmA_NPY1R; neuropeptide Y receptor type 1, member of the class A family of seven-transmembrane G protein-coupled receptors

    5. XM_038687157.1 → XP_038543085.1  neuropeptide Y receptor type 1 isoform X1

      UniProtKB/Swiss-Prot
      O02813
      UniProtKB/TrEMBL
      A0A8C0JWJ0
      Conserved Domains (1) summary
      cd15395
      Location:40 → 330
      7tmA_NPY1R; neuropeptide Y receptor type 1, member of the class A family of seven-transmembrane G protein-coupled receptors

    6. XM_038687154.1 → XP_038543082.1  neuropeptide Y receptor type 1 isoform X1

      UniProtKB/Swiss-Prot
      O02813
      UniProtKB/TrEMBL
      A0A8C0JWJ0
      Conserved Domains (1) summary
      cd15395
      Location:40 → 330
      7tmA_NPY1R; neuropeptide Y receptor type 1, member of the class A family of seven-transmembrane G protein-coupled receptors

    7. XM_038687158.1 → XP_038543086.1  neuropeptide Y receptor type 1 isoform X1

      UniProtKB/Swiss-Prot
      O02813
      UniProtKB/TrEMBL
      A0A8C0JWJ0
      Conserved Domains (1) summary
      cd15395
      Location:40 → 330
      7tmA_NPY1R; neuropeptide Y receptor type 1, member of the class A family of seven-transmembrane G protein-coupled receptors

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049275.1 Alternate UMICH_Zoey_3.1

      Range
      59574468..59575720 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

      Range
      59665153..59666405 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

      Range
      60034141..60035393 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      59946494..59947746 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O02813.2 GenPept UniProtKB/Swiss-Prot:O02813

    Gene LinkOut

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