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    rcc1.L regulator of chromosome condensation 1 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 397722, updated on 4-Nov-2024

    Summary

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    Official Symbol
    rcc1.L
    Official Full Name
    regulator of chromosome condensation 1 L homeolog
    Primary source
    Xenbase:XB-GENE-6252622
    Locus tag
    XELAEV_18012073mg
    See related
    EnsemblRapid:ENSXLAG00005031966 AllianceGenome:Xenbase:XB-GENE-6252622
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    chc1; rcc1; xrcc1; RanGEF; chc1-a; rcc1-a; rcc1-b
    Summary
    Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to act upstream of or within cell division. Predicted to be located in chromosome; cytoplasm; and nucleus. Orthologous to human RCC1 (regulator of chromosome condensation 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See rcc1.L in Genome Data Viewer
    Location:
    chromosome: 2L
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (60095758..60110655)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (57574775..57589652)

    Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene Scm polycomb group protein homolog 1 L homeolog Neighboring gene palmitoyltransferase ZDHHC20-like Neighboring gene CTP synthase 1 L homeolog Neighboring gene opioid receptor delta 1 L homeolog Neighboring gene ctranscription elongation factor A (SII), 3 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning of Xenopus RCC1 cDNA, a homolog of the human RCC1 gene: complementation of tsBN2 mutation and identification of the product. Nishitani H, et al. J Biochem, 1990 Feb. PMID 2361953
    2. Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nishiyama A, et al. Nat Commun, 2020 Mar 6. PMID 32144273, Free PMC Article
    3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    regulator of chromosome condensation
    Names
    chromosome condensation 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001087760.1 → NP_001081229.1  regulator of chromosome condensation

      See identical proteins and their annotated locations for NP_001081229.1

      Status: PROVISIONAL

      Source sequence(s)
      D00679
      UniProtKB/Swiss-Prot
      P25183
      UniProtKB/TrEMBL
      Q6IRM1
      Conserved Domains (2) summary
      pfam00415
      Location:368 → 419
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam13540
      Location:180 → 209
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      60095758..60110655
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018244855.2 → XP_018100344.1  regulator of chromosome condensation isoform X1

      UniProtKB/TrEMBL
      A0A974DMH2, Q08B75, Q6IRM1
      Related
      ENSXLAP00005095850.1, ENSXLAT00005097616.1

    2. XM_018244856.2 → XP_018100345.1  regulator of chromosome condensation isoform X1

      UniProtKB/TrEMBL
      A0A974DMH2, Q08B75, Q6IRM1
      Related
      ENSXLAP00005095764.1, ENSXLAT00005097521.1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25183.1 GenPept UniProtKB/Swiss-Prot:P25183

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.