AREG amphiregulin [Sus scrofa (pig)] - Gene

Summary

Official Symbol: AREGprovided by VGNC
Official Full Name: amphiregulinprovided by VGNC
Primary source: VGNC:VGNC:85444
See related: Ensembl:ENSSSCG00000008963
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Low expression observed in reference dataset See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	8	NC_010450.4 (70417935..70428106)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	8	NC_010450.3 (74568826..74579003)

Chromosome 8 - NC_010450.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

LH and AREG decrease BNP and CNP production in granulosa cells and down-regulate NPR2 expression in cumulus cells, which together decreased oocyte cGMP to levels that permit meiotic resumption.
Title: Epidermal growth factor-network signaling mediates luteinizing hormone regulation of BNP and CNP and their receptor NPR2 during porcine oocyte meiotic resumption.
cloning the complete coding region; comparison of endometrial amphiregulin mRNA expression in Meishan and White composite pigs
Title: Molecular cloning and endometrial expression of porcine amphiregulin.

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General gene information

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Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in epidermal growth factor receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cell population proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of epidermal growth factor-activated receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of mitotic nuclear division	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: amphiregulin

Names: amphiregulin (schwannoma-derived growth factor); amphiregulin long form

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.