AVPR2 vasopressin receptor 2 [Sus scrofa (pig)] - Gene

Summary

Official Symbol: AVPR2provided by VGNC
Official Full Name: vasopressin receptor 2provided by VGNC
Primary source: VGNC:VGNC:97898
See related: Ensembl:ENSSSCG00000012789
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Broad expression in kidney (RPKM 4.2), subcutaneous adipose (RPKM 1.5) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: X

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	X	NC_010461.5 (124638433..124640969)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	X	NC_010461.4 (142203013..142205697)

Chromosome X - NC_010461.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

AQP1, AQP2, and AQP3, and V2R expression increased with gestation age in the fetal kidney, suggesting that this induction might contribute to the maturation of urinary concentrating capacity
Title: Influence of sex on aquaporin1-4 and vasopressin V2 receptor expression in the pig kidney during development.
Type 2 vasopressin receptor (V2R) is in primary cilia of renal epithelial cells. There is also a functional cAMP-signaling pathway, which targets ciliary channel function and may help control the sensory function of the primary cilium.
Title: Vasopressin receptor-mediated functional signaling pathway in primary cilia of renal epithelial cells.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables peptide binding	IEA Inferred from Electronic Annotation more info	PubMed
enables vasopressin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of vasoconstriction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of systemic arterial blood pressure by vasopressin	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: vasopressin V2 receptor

Names: AVPR V2; V-2 lysine vasopressin receptor; V2R; antidiuretic hormone receptor; arginine vasopressin receptor 2 (nephrogenic diabetes insipidus); renal-type arginine vasopressin receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_214232.1 → NP_999397.1 vasopressin V2 receptor

See identical proteins and their annotated locations for NP_999397.1

Status: PROVISIONAL

Source sequence(s)

X71795

UniProtKB/Swiss-Prot

P32307

UniProtKB/TrEMBL

A0A4X1VIX4

Conserved Domains (1) summary

pfam00001
Location:54 → 324

7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

NC_010461.5 Reference Sscrofa11.1 Primary Assembly

Range

124638433..124640969

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_013986509.2 → XP_013841963.1 vasopressin V2 receptor isoform X1

UniProtKB/TrEMBL

A0A2C9F3C6, A0A4X1VIX4, A0A8D1A7B3

Related

ENSSSCP00000013598.2, ENSSSCT00000013981.4

Conserved Domains (1) summary

pfam00001
Location:90 → 360

7tm_1; 7 transmembrane receptor (rhodopsin family)