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    DHDH dihydrodiol dehydrogenase [ Sus scrofa (pig) ]

    Gene ID: 397337, updated on 5-Mar-2024

    Summary

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    Gene symbol
    DHDH
    Gene description
    dihydrodiol dehydrogenase
    See related
    Ensembl:ENSSSCG00000003144
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    2DD; SUS2DD
    Expression
    Ubiquitous expression in liver (RPKM 58.2), mixtures (RPKM 31.0) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 6
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 6 NC_010448.4 (54210693..54217250)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 6 NC_010448.3 (50111426..50117974, complement)

    Chromosome 6 - NC_010448.4Genomic Context describing neighboring genes Neighboring gene TUB like protein 2 Neighboring gene nucleobindin 1 Neighboring gene BCL2 associated X, apoptosis regulator Neighboring gene ferritin light chain

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Identity of dimeric dihydrodiol dehydrogenase as NADP(+)-dependent D-xylose dehydrogenase in pig liver. Aoki S, et al. Chem Biol Interact, 2001 Jan 30. PMID 11306093
    2. Cloning and sequencing of the cDNA species for mammalian dimeric dihydrodiol dehydrogenases. Arimitsu E, et al. Biochem J, 1999 Sep 15. PMID 10477285, Free PMC Article
    3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables D-xylose 1-dehydrogenase (NADP+) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in D-xylose catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
    Names
    D-xylose 1-dehydrogenase
    D-xylose-NADP dehydrogenase
    dimeric dihydrodiol dehydrogenase
    NP_999331.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214166.1 → NP_999331.1  trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

      See identical proteins and their annotated locations for NP_999331.1

      Status: PROVISIONAL

      Source sequence(s)
      AB021929
      UniProtKB/Swiss-Prot
      Q9TV69
      UniProtKB/TrEMBL
      A0A481C3F0, A0A8D1WXW0
      Related
      ENSSSCP00000003404.5, ENSSSCT00000003487.5
      Conserved Domains (2) summary
      COG0673
      Location:1 → 327
      MviM; Predicted dehydrogenase [General function prediction only]
      pfam01408
      Location:3 → 121
      GFO_IDH_MocA; Oxidoreductase family, NAD-binding Rossmann fold

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010448.4 Reference Sscrofa11.1 Primary Assembly

      Range
      54210693..54217250
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9TV69.1 GenPept UniProtKB/Swiss-Prot:Q9TV69

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials