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    KPNA5 karyopherin subunit alpha 5 [ Sus scrofa (pig) ]

    Gene ID: 397220, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KPNA5provided by VGNC
    Official Full Name
    karyopherin subunit alpha 5provided by VGNC
    Primary source
    VGNC:VGNC:89564
    See related
    Ensembl:ENSSSCG00000004262
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in kidney (RPKM 4.3), ovary (RPKM 2.1) and 8 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See KPNA5 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (44900495..44941219, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (50174005..50213653, complement)

    Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110260274 Neighboring gene 60S acidic ribosomal protein P1 pseudogene Neighboring gene family with sequence similarity 162 member B Neighboring gene zinc finger containing ubiquitin peptidase 1 Neighboring gene radial spoke head component 4A Neighboring gene uncharacterized LOC102160776

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nuclear import signal receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear localization sequence binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in NLS-bearing protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    importin subunit alpha-6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

      Range
      44900495..44941219 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001925212.7 → XP_001925247.4  importin subunit alpha-6 isoform X2

      UniProtKB/TrEMBL
      A0A4X1TD58, A0A8D1TYQ0
      Conserved Domains (5) summary
      COG5064
      Location:36 → 521
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00020
      Location:254 → 368
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam01749
      Location:9 → 105
      IBB; Importin beta binding domain
      pfam16186
      Location:467 → 511
      Arm_3; Atypical Arm repeat
      sd00043
      Location:334 → 366
      ARM; armadillo repeat [structural motif]

    2. XM_005654392.3 → XP_005654449.1  importin subunit alpha-6 isoform X1

      UniProtKB/TrEMBL
      A0A4X1TCK2, A0A8D0P4F6, A0A8D1TYQ0, F1RTU5
      Related
      ENSSSCP00000004603.3, ENSSSCT00000004711.5
      Conserved Domains (5) summary
      COG5064
      Location:36 → 521
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00020
      Location:254 → 368
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam01749
      Location:9 → 105
      IBB; Importin beta binding domain
      pfam16186
      Location:467 → 511
      Arm_3; Atypical Arm repeat
      sd00043
      Location:334 → 366
      ARM; armadillo repeat [structural motif]

    3. XM_005654393.3 → XP_005654450.1  importin subunit alpha-6 isoform X3

      UniProtKB/TrEMBL
      A0A8D1TYQ0
      Related
      ENSSSCP00000027888.3, ENSSSCT00000024609.4
      Conserved Domains (5) summary
      COG5064
      Location:33 → 518
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00020
      Location:251 → 365
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam01749
      Location:6 → 102
      IBB; Importin beta binding domain
      pfam16186
      Location:464 → 508
      Arm_3; Atypical Arm repeat
      sd00043
      Location:331 → 363
      ARM; armadillo repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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