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    AURKB aurora kinase B [ Sus scrofa (pig) ]

    Gene ID: 396955, updated on 17-Aug-2024

    Summary

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    Official Symbol
    AURKBprovided by VGNC
    Official Full Name
    aurora kinase Bprovided by VGNC
    Primary source
    VGNC:VGNC:85698
    See related
    Ensembl:ENSSSCG00000028924
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    AIM-1; ARK-2; STK-1; STK12
    Expression
    Ubiquitous expression in spleen (RPKM 4.0), lung (RPKM 3.6) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See AURKB in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 12 NC_010454.4 (53410833..53426165, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 12 NC_010454.3 (55886065..55894911, complement)

    Chromosome 12 - NC_010454.4Genomic Context describing neighboring genes Neighboring gene BLOC-1 related complex subunit 6 Neighboring gene transfer RNA threonine (anticodon AGU) Neighboring gene transfer RNA isoleucine (anticodon AAU) Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene transfer RNA aspartic acid (anticodon GUC) Neighboring gene transfer RNA proline (anticodon CGG) Neighboring gene transfer RNA threonine (anticodon AGU) Neighboring gene transfer RNA serine (anticodon AGA)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Differential gene expression during intestinal ischemia-reperfusion injury. Braun F, et al. Transplant Proc, 2002 Sep. PMID 12270407
    2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic spindle organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromosome passenger complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle microtubule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle midzone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle pole centrosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    aurora kinase B
    Names
    Serine/threonine-protein kinase 12
    aurora 1
    aurora- and IPL1-like midbody-associated protein 1
    aurora-related kinase 2
    aurora/IPL1-related kinase 2
    serine/threonine kinase 12
    serine/threonine-protein kinase 5
    serine/threonine-protein kinase aurora-B
    NP_999084.2
    XP_013845502.2
    XP_013845504.2
    XP_020921847.1
    XP_020921848.1
    XP_020921849.1
    XP_020921850.1
    XP_020921851.1
    XP_020921852.1
    XP_020921854.1
    XP_020921855.1
    XP_020921856.1
    XP_020921857.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213919.2 → NP_999084.2  aurora kinase B

      Status: VALIDATED

      Source sequence(s)
      AK234554, AK398886
      UniProtKB/Swiss-Prot
      Q7YRC7, Q9N0X0
      UniProtKB/TrEMBL
      A0A4X1VAK4
      Related
      ENSSSCP00000022968.3, ENSSSCT00000025604.4
      Conserved Domains (1) summary
      cd14117
      Location:70 → 339
      STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010454.4 Reference Sscrofa11.1 Primary Assembly

      Range
      53410833..53426165 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021066189.1 → XP_020921848.1  aurora kinase B isoform X1

      UniProtKB/TrEMBL
      A0A5G2QDV6
      Conserved Domains (1) summary
      cd14117
      Location:169 → 438
      STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins

    2. XM_013990050.2 → XP_013845504.2  aurora kinase B isoform X2

      Conserved Domains (1) summary
      cd14117
      Location:145 → 414
      STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins

    3. XM_021066188.1 → XP_020921847.1  aurora kinase B isoform X1

      UniProtKB/TrEMBL
      A0A5G2QDV6
      Conserved Domains (1) summary
      cd14117
      Location:169 → 438
      STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins

    4. XM_021066193.1 → XP_020921852.1  aurora kinase B isoform X1

      UniProtKB/TrEMBL
      A0A5G2QDV6
      Conserved Domains (1) summary
      cd14117
      Location:169 → 438
      STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins

    5. XM_021066195.1 → XP_020921854.1  aurora kinase B isoform X1

      UniProtKB/TrEMBL
      A0A5G2QDV6
      Conserved Domains (1) summary
      cd14117
      Location:169 → 438
      STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins

    6. XM_021066190.1 → XP_020921849.1  aurora kinase B isoform X1

      UniProtKB/TrEMBL
      A0A5G2QDV6
      Related
      ENSSSCP00000061822.1, ENSSSCT00000090078.2
      Conserved Domains (1) summary
      cd14117
      Location:169 → 438
      STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins

    7. XM_021066191.1 → XP_020921850.1  aurora kinase B isoform X1

      UniProtKB/TrEMBL
      A0A5G2QDV6
      Conserved Domains (1) summary
      cd14117
      Location:169 → 438
      STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins

    8. XM_021066192.1 → XP_020921851.1  aurora kinase B isoform X1

      UniProtKB/TrEMBL
      A0A5G2QDV6
      Conserved Domains (1) summary
      cd14117
      Location:169 → 438
      STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins

    9. XM_021066198.1 → XP_020921857.1  aurora kinase B isoform X5

      UniProtKB/TrEMBL
      A0A4X1V985
      Conserved Domains (1) summary
      cd14117
      Location:121 → 390
      STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins

    10. XM_021066197.1 → XP_020921856.1  aurora kinase B isoform X4

      Conserved Domains (1) summary
      cl21453
      Location:21 → 187
      PKc_like; Protein Kinases, catalytic domain

    11. XM_021066196.1 → XP_020921855.1  aurora kinase B isoform X3

      UniProtKB/TrEMBL
      A0A8D1W4X7
      Conserved Domains (1) summary
      cd14117
      Location:29 → 298
      STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins

    12. XM_013990048.2 → XP_013845502.2  aurora kinase B isoform X3

      UniProtKB/TrEMBL
      A0A8D1W4X7
      Conserved Domains (1) summary
      cd14117
      Location:29 → 298
      STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9N0X0.2 GenPept UniProtKB/Swiss-Prot:Q9N0X0

    Gene LinkOut

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