CAPZA1 capping actin protein of muscle Z-line alpha subunit 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: CAPZA1provided by CGNC
Full Name: capping actin protein of muscle Z-line alpha subunit 1provided by CGNC
Primary source: CGNC:1070
See related: Ensembl:ENSGALG00010027457
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 26

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	26	NC_052557.1 (3573796..3583769)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	26	NC_052598.1 (3542070..3552060)

Chromosome 26 - NC_052557.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CARMIL proteins down-regulate CP by affecting its conformational dynamics.
Title: Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition.
actin-capping protein binds to the filament barbed end of myotrophin/V-1
Title: Binding of myotrophin/V-1 to actin-capping protein: implications for how capping protein binds to the filament barbed end.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables actin filament binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in actin cytoskeleton organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in barbed-end actin filament capping	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of F-actin capping protein complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in actin cortical patch	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: F-actin-capping protein subunit alpha-1

Names: actin-capping protein (CapZ 36/32) alpha subunit; beta-actinin subunit I; capZ 36/32; capping protein (actin filament) muscle Z-line, alpha 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.