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    LPL lipoprotein lipase [ Gallus gallus (chicken) ]

    Gene ID: 396219, updated on 10-Oct-2024

    Summary

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    Symbol
    LPLprovided by CGNC
    Full Name
    lipoprotein lipaseprovided by CGNC
    Primary source
    CGNC:11495
    See related
    Ensembl:ENSGALG00010013954
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See LPL in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (55215002..55232438, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (55215002..55232438, complement)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene neuregulin 1 Neighboring gene uncharacterized LOC112530610 Neighboring gene pleckstrin and Sec7 domain containing 3 Neighboring gene uncharacterized LOC121108270 Neighboring gene nipsnap homolog 3A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Avian adipose lipoprotein lipase: cDNA sequence and reciprocal regulation of mRNA levels in adipose and heart. Cooper DA, et al. Biochim Biophys Acta, 1989 Jun 1. PMID 2719965
    2. Occurrence of sulfate in an asparagine-linked complex oligosaccharide of chicken adipose lipoprotein lipase. Hoogewerf AJ, et al. J Biol Chem, 1991 Jan 15. PMID 1985932
    3. The structure and complete nucleotide sequence of the avian lipoprotein lipase gene. Cooper DA, et al. Biochim Biophys Acta, 1992 Jan 6. PMID 1730055
    4. High-resolution melting curve analysis of the ADSL and LPL genes and their correlation with meat quality and blood parameters in chickens. Zhang XD, et al. Genet Mol Res, 2015 Mar 20. PMID 25867349
    5. Biochemical characterization, cloning, and molecular modelling of chicken pancreatic lipase. Fendri A, et al. Arch Biochem Biophys, 2006 Jul 15. PMID 16780787

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Authors...analyzed polymorphisms in the ADSL and LPL genes using the high-resolution melting curve method.
      Title: High-resolution melting curve analysis of the ADSL and LPL genes and their correlation with meat quality and blood parameters in chickens.
    2. Studies identify HTGL, EL, Lipase H, and CEL in a pre-mammalian species and reveals novel details about specific features of the expression of these important molecules in lipid metabolism.
      Title: Tissue distribution of lipase genes related to triglyceride metabolism in laying hens (Gallus gallus).
    3. LPL was characterized biochemically and by molecular cloning.
      Title: Biochemical characterization, cloning, and molecular modelling of chicken pancreatic lipase.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables apolipoprotein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lipoprotein lipase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lipoprotein lipase
    Names
    adipose lipoprotein lipase
    phospholipase A1
    triacylglycerol lipase
    NP_990613.1
    XP_015135900.1
    XP_046761227.1
    XP_046790825.1
    XP_046790826.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205282.2 → NP_990613.1  lipoprotein lipase precursor

      See identical proteins and their annotated locations for NP_990613.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000095
      UniProtKB/Swiss-Prot
      P11602
      UniProtKB/TrEMBL
      J7FPX4, Q9PSV4
      Related
      ENSGALP00010019747.1, ENSGALT00010033474.1
      Conserved Domains (3) summary
      TIGR03230
      Location:33 → 473
      lipo_lipase; lipoprotein lipase
      cd00707
      Location:37 → 334
      Pancreat_lipase_like; Pancreatic lipase-like enzymes. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the ...
      cd01758
      Location:341 → 465
      PLAT_LPL; PLAT/ LH2 domain present in lipoprotein lipase (LPL). LPL is a key enzyme in catabolism of plasma lipoprotein triglycerides (TGs) and has therefeore has a profound influence on triglyceride and high-density lipoprotein (HDL) cholesterol levels in the ...

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      55215002..55232438 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046905271.1 → XP_046761227.1  lipoprotein lipase isoform X2

    2. XM_015280414.4 → XP_015135900.1  lipoprotein lipase isoform X1

      UniProtKB/TrEMBL
      J7FPX4, Q9PSV4
      Conserved Domains (3) summary
      TIGR03230
      Location:34 → 474
      lipo_lipase; lipoprotein lipase
      cd00707
      Location:38 → 335
      Pancreat_lipase_like; Pancreatic lipase-like enzymes. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the ...
      cd01758
      Location:342 → 466
      PLAT_LPL; PLAT/ LH2 domain present in lipoprotein lipase (LPL). LPL is a key enzyme in catabolism of plasma lipoprotein triglycerides (TGs) and has therefeore has a profound influence on triglyceride and high-density lipoprotein (HDL) cholesterol levels in the ...

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      55215002..55232438 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046934870.1 → XP_046790826.1  lipoprotein lipase isoform X2

    2. XM_046934869.1 → XP_046790825.1  lipoprotein lipase isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P11602.1 GenPept UniProtKB/Swiss-Prot:P11602

    Gene LinkOut

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