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    RAPSN receptor associated protein of the synapse [ Gallus gallus (chicken) ]

    Gene ID: 395986, updated on 10-Oct-2024

    Summary

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    Symbol
    RAPSNprovided by CGNC
    Full Name
    receptor associated protein of the synapseprovided by CGNC
    Primary source
    CGNC:6136
    See related
    Ensembl:ENSGALG00010022229
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See RAPSN in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (22381282..22403673)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (22348869..22371232)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene kelch repeat and BTB domain containing 4 Neighboring gene protein tyrosine phosphatase, mitochondrial 1 Neighboring gene CUGBP Elav-like family member 1 Neighboring gene uncharacterized LOC121111002 Neighboring gene proteasome 26S subunit, ATPase 3 Neighboring gene transmembrane protein 178B-like Neighboring gene microRNA 1725

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chick ciliary ganglion neurons contain transcripts coding for acetylcholine receptor-associated protein at synapses (rapsyn). Burns AL, et al. J Neurosci, 1997 Jul 1. PMID 9185539, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acetylcholine receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein-membrane adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    43 kDa receptor-associated protein of the synapse
    Names
    43 kDa postsynaptic protein
    acetylcholine receptor-associated 43 kDa protein
    rapsyn
    receptor-associated protein of the synapse, 43kD

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001396392.1 → NP_001383321.1  43 kDa receptor-associated protein of the synapse isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000214
      UniProtKB/Swiss-Prot
      O42393
      Conserved Domains (4) summary
      COG0457
      Location:11 → 190
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:114 → 142
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:155 → 229
      TPR_12; Tetratricopeptide repeat
      cd16478
      Location:311 → 355
      RING-H2_Rapsyn; RING finger, H2 subclass, found in 43 kDa receptor-associated protein of the synapse (Rapsyn) and similar proteins

    2. NM_001396393.1 → NP_001383322.1  43 kDa receptor-associated protein of the synapse isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000214
      UniProtKB/Swiss-Prot
      O42393
      Conserved Domains (3) summary
      sd00006
      Location:153 → 181
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:151 → 225
      TPR_12; Tetratricopeptide repeat
      cd16478
      Location:307 → 351
      RING-H2_Rapsyn; RING finger, H2 subclass, found in 43 kDa receptor-associated protein of the synapse (Rapsyn) and similar proteins

    3. NM_205097.2 → NP_990428.2  43 kDa receptor-associated protein of the synapse isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000214
      UniProtKB/Swiss-Prot
      O42393
      Related
      ENSGALP00010032625.1, ENSGALT00010054094.1
      Conserved Domains (4) summary
      COG0457
      Location:9 → 239
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:84 → 111
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:204 → 278
      TPR_12; Tetratricopeptide repeat
      cd16478
      Location:360 → 404
      RING-H2_Rapsyn; RING finger, H2 subclass, found in 43 kDa receptor-associated protein of the synapse (Rapsyn) and similar proteins

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      22381282..22403673
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015286981.4 → XP_015142467.1  43 kDa receptor-associated protein of the synapse isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZMF5
      Conserved Domains (6) summary
      COG0457
      Location:1 → 257
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:102 → 129
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:222 → 296
      TPR_12; Tetratricopeptide repeat
      pfam13639
      Location:381 → 421
      zf-RING_2; Ring finger domain
      cl14649
      Location:162 → 254
      BRO1_Alix_like; Protein-interacting Bro1-like domain of mammalian Alix and related domains
      cl24038
      Location:9 → 98
      SNAP; Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family

    2. XM_046941468.1 → XP_046797424.1  43 kDa receptor-associated protein of the synapse isoform X3

    3. XM_046941467.1 → XP_046797423.1  43 kDa receptor-associated protein of the synapse isoform X2

    4. XM_046941469.1 → XP_046797425.1  43 kDa receptor-associated protein of the synapse isoform X4

    5. XM_046941470.1 → XP_046797426.1  43 kDa receptor-associated protein of the synapse isoform X5

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      22348869..22371232
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046917880.1 → XP_046773836.1  43 kDa receptor-associated protein of the synapse isoform X1

    2. XM_046917882.1 → XP_046773838.1  43 kDa receptor-associated protein of the synapse isoform X3

    3. XM_046917881.1 → XP_046773837.1  43 kDa receptor-associated protein of the synapse isoform X2

    4. XM_046917883.1 → XP_046773839.1  43 kDa receptor-associated protein of the synapse isoform X4

    5. XM_046917884.1 → XP_046773840.1  43 kDa receptor-associated protein of the synapse isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O42393.3 GenPept UniProtKB/Swiss-Prot:O42393

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