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    PROK2 prokineticin 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 387602, updated on 4-Oct-2024

    Summary

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    Official Symbol
    PROK2provided by VGNC
    Official Full Name
    prokineticin 2provided by VGNC
    Primary source
    VGNC:VGNC:33362
    See related
    BGD:BT24900; Ensembl:ENSBTAG00000019330
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    Bv8
    Orthologs
    human mouse all
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    Genomic context

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    See PROK2 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (29859669..29887673)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112443494 Neighboring gene uncharacterized LOC112443517 Neighboring gene G protein-coupled receptor 27 Neighboring gene uncharacterized LOC132343536 Neighboring gene eukaryotic translation initiation factor 4E family member 3 Neighboring gene forkhead box P1 Neighboring gene microRNA mir-1284

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitogenic functions of endocrine gland-derived vascular endothelial growth factor and Bombina variegata 8 on steroidogenic adrenocortical cells. Keramidas M, et al. J Endocrinol, 2008 Mar. PMID 18310443
    2. The AVIT protein family. Secreted cysteine-rich vertebrate proteins with diverse functions. Kaser A, et al. EMBO Rep, 2003 May. PMID 12728244, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. EG-VEGF/PK1 and Bv8/PK2 thus represent new regulatory peptides acting as autocrine mitogens for endocrine cells
      Title: Mitogenic functions of endocrine gland-derived vascular endothelial growth factor and Bombina variegata 8 on steroidogenic adrenocortical cells.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    prokineticin-2
    Names
    PK2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199445.1 → NP_955516.1  prokineticin-2 precursor

      See identical proteins and their annotated locations for NP_955516.1

      Status: PROVISIONAL

      Source sequence(s)
      AY192557
      UniProtKB/Swiss-Prot
      Q863H4, Q863H5
      Related
      ENSBTAP00000025742.6, ENSBTAT00000025742.7
      Conserved Domains (1) summary
      pfam06607
      Location:24 → 125
      Prokineticin; Prokineticin

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      29859669..29887673
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024982410.2 → XP_024838178.1  prokineticin-2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TDW8
      Related
      ENSBTAP00000095096.1, ENSBTAT00000097412.1
      Conserved Domains (1) summary
      pfam06607
      Location:24 → 105
      Prokineticin

    RNA

    1. XR_009492257.1 RNA Sequence

    2. XR_009492258.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q863H5.1 GenPept UniProtKB/Swiss-Prot:Q863H5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials