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    robl62A robl62A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38170, updated on 18-Sep-2024

    Summary

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    Official Symbol
    robl62Aprovided by FlyBase
    Official Full Name
    robl62Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028567
    Locus tag
    Dmel_CG1014
    See related
    AllianceGenome:FB:FBgn0028567
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1014; Dmel\CG1014; rob162A
    Summary
    Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Predicted to be part of cytoplasmic dynein complex. Predicted to be active in centrosome and cytoplasm. Is expressed in primary spermatocyte and spermatozoon. Orthologous to human DYNLRB1 (dynein light chain roadblock-type 1) and DYNLRB2 (dynein light chain roadblock-type 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See robl62A in Genome Data Viewer
    Location:
    62A2-62A2; 3-0.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1477619..1478369)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1477619..1478369)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Protein tyrosine phosphatase 61F Neighboring gene ncRNA Neighboring gene rhomboid Neighboring gene small non-coding RNA:CR43701 Neighboring gene N(alpha)-acetyltransferase 30 B Neighboring gene stem cell tumor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular mechanisms of gene regulation during Drosophila spermatogenesis. White-Cooper H. Reproduction, 2010 Jan. PMID 19755484
    2. Alkaline Ceramidase Mediates the Oxidative Stress Response in Drosophila melanogaster Through Sphingosine. Zhang CH, et al. J Insect Sci, 2019 May 1. PMID 31115476, Free PMC Article
    3. The Drosophila female germline stem cell lineage acts to spatially restrict DPP function within the niche. Liu M, et al. Sci Signal, 2010 Jul 27. PMID 20664066
    4. Many P-element insertions affect wing shape in Drosophila melanogaster. Weber K, et al. Genetics, 2005 Mar. PMID 15545659, Free PMC Article
    5. Genome-wide identification of in vivo Drosophila Engrailed-binding DNA fragments and related target genes. Solano PJ, et al. Development, 2003 Apr. PMID 12588842

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables dynein intermediate chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables dynein intermediate chain binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in microtubule-based movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in microtubule-based movement ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytoplasmic dynein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytoplasmic dynein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of dynein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    robl62A
    Names
    CG1014-PA
    CG1014-PB
    robl62A-PA
    robl62A-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1477619..1478369
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138266.2 → NP_612110.1  robl62A, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_612110.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W0F0
      Related
      FBpp0072579, FBtr0072695
      Conserved Domains (1) summary
      smart00960
      Location:24 → 103
      Robl_LC7; Roadblock/LC7 domain

    2. NM_001274327.1 → NP_001261256.1  robl62A, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261256.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W0F0
      Conserved Domains (1) summary
      smart00960
      Location:24 → 103
      Robl_LC7; Roadblock/LC7 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W0F0 Q9W0F0

    Gene LinkOut

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