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    THBS1 thrombospondin 1 [ Gallus gallus (chicken) ]

    Gene ID: 373987, updated on 17-Aug-2024

    Summary

    Official Symbol
    THBS1provided by CGNC
    Official Full Name
    thrombospondin 1provided by CGNC
    Primary source
    CGNC:48991
    See related
    Ensembl:ENSGALG00010021087
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    thrombospondin-1
    Orthologs
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    Genomic context

    See THBS1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (29117435..29133073, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (29098706..29114345, complement)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110826 Neighboring gene fibrous sheath interacting protein 1 Neighboring gene uncharacterized LOC107053494 Neighboring gene uncharacterized LOC121110827 Neighboring gene katanin regulatory subunit B1 like 1

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in negative regulation of angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001199453.2NP_001186382.1  thrombospondin-1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000215
      UniProtKB/TrEMBL
      A0A8V0ZHF5
      Related
      ENSGALP00010030233.1, ENSGALT00010051042.1
      Conserved Domains (10) summary
      smart00209
      Location:443495
      TSP1; Thrombospondin type 1 repeats
      sd00001
      Location:850887
      TSP3; TSP3 repeat_long [structural motif]
      sd00002
      Location:792826
      TSP3; TSP3 repeat_long [structural motif]
      sd00003
      Location:696731
      TSP3_1C; TSP3 repeat_1C [structural motif]
      pfam00090
      Location:388433
      TSP_1; Thrombospondin type 1 domain
      pfam00093
      Location:323377
      VWC; von Willebrand factor type C domain
      pfam02412
      Location:851887
      TSP_3; Thrombospondin type 3 repeat
      pfam05735
      Location:9771174
      TSP_C; Thrombospondin C-terminal region
      pfam12947
      Location:655694
      EGF_3; EGF domain
      cl22861
      Location:28226
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      29117435..29133073 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      29098706..29114345 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)