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    Ipk1 Inositol phosphate kinase 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37360, updated on 18-Sep-2024

    Summary

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    Official Symbol
    Ipk1provided by FlyBase
    Official Full Name
    Inositol phosphate kinase 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0050295
    Locus tag
    Dmel_CG30295
    See related
    AllianceGenome:FB:FBgn0050295
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15228; CG15229; CG15230; CG30295; Dmel\CG30295; dmIpk1
    Summary
    Enables inositol pentakisphosphate 2-kinase activity. Involved in inositol phosphate biosynthetic process and inositol phosphorylation. Predicted to be active in nucleus. Is expressed in organism. Orthologous to human IPPK (inositol-pentakisphosphate 2-kinase). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See Ipk1 in Genome Data Viewer
    Location:
    57B3-57B4; 2-92 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20870791..20879145)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16758296..16766650)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Daisho1 Neighboring gene Daisho2 Neighboring gene Calcium and integrin binding family member 2 Neighboring gene orthopedia Neighboring gene antisense RNA:CR43160

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Inositol phosphate kinase 2 is required for imaginal disc development in Drosophila. Seeds AM, et al. Proc Natl Acad Sci U S A, 2015 Dec 22. PMID 26647185, Free PMC Article
    2. A molecular basis for inositol polyphosphate synthesis in Drosophila melanogaster. Seeds AM, et al. J Biol Chem, 2004 Nov 5. PMID 15322119
    3. Transposition of the vertebrate Tol2 transposable element in Drosophila melanogaster. Urasaki A, et al. Gene, 2008 Dec 1. PMID 18775483
    4. The protein kinase CK2 substrate Jabba modulates lipid metabolism during Drosophila oogenesis. McMillan EA, et al. J Biol Chem, 2018 Feb 23. PMID 29326167, Free PMC Article
    5. Copper homeostasis gene discovery in Drosophila melanogaster. Norgate M, et al. Biometals, 2007 Jun. PMID 17216353

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in inositol phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in inositol phosphate biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    inositol phosphate kinase 1
    Names
    CG30295-PA
    CG30295-PB
    CG30295-PC
    CG30295-PD
    Ipk1-PA
    Ipk1-PB
    Ipk1-PC
    Ipk1-PD
    NP_001097387.1
    NP_001261111.1
    NP_001286649.1
    NP_611522.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20870791..20879145
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001103917.3 → NP_001097387.1  inositol phosphate kinase 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097387.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DYK1
      Conserved Domains (1) summary
      pfam06090
      Location:51 → 332
      Ins_P5_2-kin; Inositol-pentakisphosphate 2-kinase

    2. NM_001274182.2 → NP_001261111.1  inositol phosphate kinase 1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261111.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KEV9
      Conserved Domains (1) summary
      pfam06090
      Location:51 → 332
      Ins_P5_2-kin; Inositol-pentakisphosphate 2-kinase

    3. NM_137678.3 → NP_611522.1  inositol phosphate kinase 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611522.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95R36, Q9W2Q7
      Related
      FBpp0071444
      Conserved Domains (1) summary
      pfam06090
      Location:51 → 332
      Ins_P5_2-kin; Inositol-pentakisphosphate 2-kinase

    4. NM_001299720.1 → NP_001286649.1  inositol phosphate kinase 1, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286649.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LH15
      Conserved Domains (1) summary
      pfam06090
      Location:85 → 192
      Ins_P5_2-kin; Inositol-pentakisphosphate 2-kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KEV9 A0A0B4KEV9
    A0A0B4LH15 A0A0B4LH15
    A8DYK1 A8DYK1
    Q9W2Q7.2 Q9W2Q7

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