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    G6PC3 glucose-6-phosphatase catalytic subunit 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 369023, updated on 4-Oct-2024

    Summary

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    Official Symbol
    G6PC3provided by VGNC
    Official Full Name
    glucose-6-phosphatase catalytic subunit 3provided by VGNC
    Primary source
    VGNC:VGNC:29180
    See related
    BGD:BT11410; Ensembl:ENSBTAG00000016253
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See G6PC3 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (43907216..43911994)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene N-acetylglutamate synthase Neighboring gene transmembrane protein 101 Neighboring gene LSM12 homolog Neighboring gene histone deacetylase 5 Neighboring gene uncharacterized LOC132343083 Neighboring gene homologous recombination factor with OB-fold

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC140735

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glucose-6-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in gluconeogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glucose 6-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glucose-6-phosphatase 3
    Names
    G-6-Pase 3
    G6Pase 3
    glucose-6-phosphatase catalytic subunit-related
    NP_899208.2
    XP_024835454.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183364.3 → NP_899208.2  glucose-6-phosphatase 3

      See identical proteins and their annotated locations for NP_899208.2

      Status: PROVISIONAL

      Source sequence(s)
      BC118357
      UniProtKB/Swiss-Prot
      Q148G2, Q7YSF2
      Related
      ENSBTAP00000021621.3, ENSBTAT00000021621.5
      Conserved Domains (1) summary
      cd03381
      Location:38 → 270
      PAP2_glucose_6_phosphatase; PAP2_like proteins, glucose-6-phosphatase subfamily. Glucose-6-phosphatase converts glucose-6-phosphate into free glucose and is active in the lumen of the endoplasmic reticulum, where it is bound to the membrane. The generation of free glucose is an ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      43907216..43911994
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024979686.2 → XP_024835454.1  glucose-6-phosphatase 3 isoform X1

      Conserved Domains (1) summary
      cl00474
      Location:38 → 141
      PAP2_like; PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q148G2.1 GenPept UniProtKB/Swiss-Prot:Q148G2

    Gene LinkOut

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