Nanos1 nanos C2HC-type zinc finger 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Nanos1provided by RGD
Official Full Name: nanos C2HC-type zinc finger 1provided by RGD
Primary source: RGD:1308194
See related: EnsemblRapid:ENSRNOG00000082455 AllianceGenome:RGD:1308194
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable enzyme activator activity and mRNA binding activity. Predicted to be involved in epithelial cell migration; oogenesis; and post-transcriptional regulation of gene expression. Predicted to act upstream of or within several processes, including cerebellar neuron development; regulation of cell growth; and tissue homeostasis. Predicted to be located in cytoplasm. Predicted to be active in perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in spermatogenic failure 12. Orthologous to human NANOS1 (nanos C2HC-type zinc finger 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs: human mouse all
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Genomic context

Location:: 1q55

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (269883713..269887611)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (259897663..259901561)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (282134676..282140370)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The RNA-binding protein NANOS1 controls hippocampal synaptogenesis.
Title: The RNA-binding protein NANOS1 controls hippocampal synaptogenesis.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables enzyme activator activity	ISO Inferred from Sequence Orthology more info
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cell migration	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within cerebellar neuron development	ISO Inferred from Sequence Orthology more info
involved_in epithelial cell migration	ISO Inferred from Sequence Orthology more info
involved_in mRNA destabilization	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of translation	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of translation	ISO Inferred from Sequence Orthology more info
involved_in oogenesis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within post-transcriptional regulation of gene expression	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of cell growth	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within tissue homeostasis	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
is_active_in perinuclear region of cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in perinuclear region of cytoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: nanos homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.