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    Lrrc63 leucine rich repeat containing 63 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 364427, updated on 18-Sep-2024

    Summary

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    Official Symbol
    Lrrc63provided by RGD
    Official Full Name
    leucine rich repeat containing 63provided by RGD
    Primary source
    RGD:1559507
    See related
    EnsemblRapid:ENSRNOG00000038291 AllianceGenome:RGD:1559507
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to human LRRC63 (leucine rich repeat containing 63). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward (RPKM 76.3) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lrrc63 in Genome Data Viewer
    Location:
    15q11
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (56809629..56846831, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (50400199..50437321, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (57132507..57170467, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeats and calponin homology domain containing 1 Neighboring gene uncharacterized LOC134482151 Neighboring gene uncharacterized LOC108352942 Neighboring gene rubicon like autophagy enhancer Neighboring gene uncharacterized LOC120097039 Neighboring gene establishment of cohesion 1 homolog 2 (S. cerevisiae), pseudogene 2 Neighboring gene lymphocyte cytosolic protein 1 Neighboring gene tRNA methyltransferase 10A, pseudogene 1 Neighboring gene carboxypeptidase B2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 63

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024803.1 → NP_001019974.1  leucine-rich repeat-containing protein 63

      See identical proteins and their annotated locations for NP_001019974.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097406
      UniProtKB/Swiss-Prot
      Q4V8G0
      UniProtKB/TrEMBL
      A0A0G2K2X5, A6HTS3
      Related
      ENSRNOP00000055096.2, ENSRNOT00000058294.4
      Conserved Domains (2) summary
      COG4886
      Location:349 → 479
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:322 → 353
      LRR_RI; leucine-rich repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      56809629..56846831 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006252326.5 → XP_006252388.1  leucine-rich repeat-containing protein 63 isoform X1

      See identical proteins and their annotated locations for XP_006252388.1

      UniProtKB/Swiss-Prot
      Q4V8G0
      UniProtKB/TrEMBL
      A0A0G2K2X5, A6HTS3
      Conserved Domains (2) summary
      COG4886
      Location:349 → 479
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:322 → 353
      LRR_RI; leucine-rich repeat [structural motif]

    2. XM_006252325.5 → XP_006252387.1  leucine-rich repeat-containing protein 63 isoform X1

      See identical proteins and their annotated locations for XP_006252387.1

      UniProtKB/Swiss-Prot
      Q4V8G0
      UniProtKB/TrEMBL
      A0A0G2K2X5, A6HTS3
      Conserved Domains (2) summary
      COG4886
      Location:349 → 479
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:322 → 353
      LRR_RI; leucine-rich repeat [structural motif]

    3. XM_006252327.5 → XP_006252389.1  leucine-rich repeat-containing protein 63 isoform X1

      See identical proteins and their annotated locations for XP_006252389.1

      UniProtKB/Swiss-Prot
      Q4V8G0
      UniProtKB/TrEMBL
      A0A0G2K2X5, A6HTS3
      Conserved Domains (2) summary
      COG4886
      Location:349 → 479
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:322 → 353
      LRR_RI; leucine-rich repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V8G0.1 GenPept UniProtKB/Swiss-Prot:Q4V8G0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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