Slc39a10 solute carrier family 39 member 10 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc39a10provided by RGD
Official Full Name: solute carrier family 39 member 10provided by RGD
Primary source: RGD:1307321
See related: EnsemblRapid:ENSRNOG00000011677 AllianceGenome:RGD:1307321
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable monoatomic cation:bicarbonate symporter activity and zinc ion transmembrane transporter activity. Predicted to be involved in epithelial to mesenchymal transition; intracellular monoatomic cation homeostasis; and zinc ion import across plasma membrane. Predicted to act upstream of or within several processes, including intracellular zinc ion homeostasis; positive regulation of B cell proliferation; and positive regulation of B cell receptor signaling pathway. Predicted to be located in apical plasma membrane. Predicted to be active in plasma membrane. Orthologous to human SLC39A10 (solute carrier family 39 member 10). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 153.6), Testes (RPKM 58.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 9q31

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	9	NC_086027.1 (62331281..62454754)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	9	NC_051344.1 (54836841..54960325)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	9	NC_005108.4 (59947562..60070549)

Chromosome 9 - NC_086027.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Chronic Running Exercise Regulates Cytotoxic Cell Functions and Zinc Transporter SLC39A10/ZIP10 Levels in Diabetic Rats.
Title: Chronic Running Exercise Regulates Cytotoxic Cell Functions and Zinc Transporter SLC39A10/ZIP10 Levels in Diabetic Rats.

Submit: New GeneRIF Correction

General gene information

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Markers

RH143016 (e-PCR)
- UniSTS:232263

RH137127 (e-PCR)
- UniSTS:219215

DNAH7__4760 (e-PCR)
- UniSTS:463254

RH127346 (e-PCR)
- UniSTS:210656

RH140829 (e-PCR)
- UniSTS:210656

BF413432 (e-PCR)
- UniSTS:248558

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables monoatomic cation:bicarbonate symporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein tyrosine phosphatase activator activity	ISO Inferred from Sequence Orthology more info
enables zinc ion transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion transmembrane transporter activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in bicarbonate transport	IEA Inferred from Electronic Annotation more info
involved_in epithelial to mesenchymal transition	ISO Inferred from Sequence Orthology more info
involved_in intracellular monoatomic cation homeostasis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within intracellular zinc ion homeostasis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within negative regulation of B cell apoptotic process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of B cell proliferation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of B cell receptor signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in zinc ion import across plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within zinc ion import across plasma membrane	ISO Inferred from Sequence Orthology more info
involved_in zinc ion transmembrane transport	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in apical plasma membrane	ISO Inferred from Sequence Orthology more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: zinc transporter ZIP10

Names: solute carrier family 39 (zinc transporter), member 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.