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    C8h11orf54 similar to human chromosome 11 open reading frame 54 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363016, updated on 2-Nov-2024

    Summary

    Official Symbol
    C8h11orf54provided by RGD
    Official Full Name
    similar to human chromosome 11 open reading frame 54provided by RGD
    Primary source
    RGD:1309534
    See related
    EnsemblRapid:ENSRNOG00000010887 AllianceGenome:RGD:1309534
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309534
    Summary
    Predicted to enable hydrolase activity, acting on ester bonds and zinc ion binding activity. Predicted to be located in nuclear body. Predicted to be active in nucleus. Orthologous to human C11orf54 (chromosome 11 open reading frame 54). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 1626.4), Liver (RPKM 287.0) and 3 other tissues See more
    Orthologs
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    Genomic context

    See C8h11orf54 in Genome Data Viewer
    Location:
    8q12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (20405240..20427811, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (12123839..12146412, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (13838549..13861120, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 17 Neighboring gene uncharacterized LOC102552229 Neighboring gene TATA-box binding protein associated factor, RNA polymerase I subunit D Neighboring gene small nucleolar RNA SNORA40 Neighboring gene small nucleolar RNA, H/ACA box 18

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables hydrolase activity, acting on ester bonds IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables hydrolase activity, acting on ester bonds IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity, acting on ester bonds ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in nuclear body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ester hydrolase C11orf54 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014206.1NP_001014228.1  ester hydrolase C11orf54 homolog

      See identical proteins and their annotated locations for NP_001014228.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085915
      UniProtKB/Swiss-Prot
      Q5U2Q3
      UniProtKB/TrEMBL
      A0A8I5ZKD7, A6JNB5, A6JNB6
      Related
      ENSRNOP00000014496.7, ENSRNOT00000014496.8
      Conserved Domains (1) summary
      cd17298
      Location:14304
      DUF1907; proteins similar to putative ester hydrolase C11orf54/PTD012

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      20405240..20427811 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265683.1XP_063121753.1  ester hydrolase C11orf54 homolog isoform X1