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    Gpr21 G protein-coupled receptor 21 [ Mus musculus (house mouse) ]

    Gene ID: 338346, updated on 2-Nov-2024

    Summary

    Official Symbol
    Gpr21provided by MGI
    Official Full Name
    G protein-coupled receptor 21provided by MGI
    Primary source
    MGI:MGI:2441890
    See related
    Ensembl:ENSMUSG00000053164 AllianceGenome:MGI:2441890
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C230004C13Rik
    Summary
    Predicted to enable trace-amine receptor activity. Acts upstream of or within glucose homeostasis; negative regulation of insulin receptor signaling pathway; and regulation of growth. Predicted to be active in plasma membrane. Is expressed in cerebral cortex; cerebral cortex marginal layer; cerebral cortex subventricular zone; and cortical plate. Orthologous to human GPR21 (G protein-coupled receptor 21). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in whole brain E14.5 (RPKM 2.9), CNS E18 (RPKM 2.9) and 14 other tissues See more
    Orthologs
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    Genomic context

    See Gpr21 in Genome Data Viewer
    Location:
    2 B; 2 24.19 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (37406638..37409293)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (37516626..37519281)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1004 Neighboring gene zinc finger and BTB domain containing 26 Neighboring gene RAB GTPase activating protein 1 Neighboring gene nucleoporin 37 pseudogene Neighboring gene spermatid perinuclear RNA binding protein Neighboring gene zinc finger protein 609 pseudogene Neighboring gene microRNA 5128

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2)  1 citation

    Pathways from PubChem

    General protein information

    Preferred Names
    probable G-protein coupled receptor 21
    Names
    G protein-coupled receptor GPR21

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177383.4NP_796357.1  probable G-protein coupled receptor 21

      See identical proteins and their annotated locations for NP_796357.1

      Status: PROVISIONAL

      Source sequence(s)
      AK048682
      Consensus CDS
      CCDS16004.1
      UniProtKB/Swiss-Prot
      Q80T46, Q8BX79
      Related
      ENSMUSP00000066449.7, ENSMUST00000065441.7
      Conserved Domains (2) summary
      pfam00001
      Location:45304
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:37216
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      37406638..37409293
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)