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    COL4A3 collagen type IV alpha 3 chain [ Bos taurus (domestic cattle) ]

    Gene ID: 317711, updated on 4-Oct-2024

    Summary

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    Official Symbol
    COL4A3provided by VGNC
    Official Full Name
    collagen type IV alpha 3 chainprovided by VGNC
    Primary source
    VGNC:VGNC:55339
    See related
    BGD:BT28492; Ensembl:ENSBTAG00000021316
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See COL4A3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    52
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (115318013..115478018)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein eL21-like Neighboring gene rhomboid domain containing 1 Neighboring gene collagen type IV alpha 4 chain Neighboring gene mitochondrial fission factor Neighboring gene transmembrane 4 L six family member 20

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of the Goodpasture antigen as the alpha 3(IV) chain of collagen IV. Saus J, et al. J Biol Chem, 1988 Sep 15. PMID 3417661
    2. Use of the polymerase chain reaction to clone and sequence a cDNA encoding the bovine alpha 3 chain of type IV collagen. Morrison KE, et al. J Biol Chem, 1991 Jan 5. PMID 1985905
    3. Localization of the Goodpasture epitope to a novel chain of basement membrane collagen. Butkowski RJ, et al. J Biol Chem, 1987 Jun 5. PMID 2438283
    4. Glomerular basement membrane. Identification of a fourth chain, alpha 4, of type IV collagen. Gunwar S, et al. J Biol Chem, 1990 Apr 5. PMID 2318822
    5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    collagen alpha-3(IV) chain
    Names
    collagen, type IV, alpha 3 (Goodpasture antigen)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166529.2 → NP_001160001.2  collagen alpha-3(IV) chain precursor

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000002
      UniProtKB/TrEMBL
      F1MZU6
      Related
      ENSBTAP00000028418.5, ENSBTAT00000028418.7
      Conserved Domains (2) summary
      pfam01391
      Location:557 → 615
      Collagen; Collagen triple helix repeat (20 copies)
      pfam01413
      Location:1446 → 1552
      C4; C-terminal tandem repeated domain in type 4 procollagen

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      115318013..115478018
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q28084.1 GenPept UniProtKB/Swiss-Prot:Q28084

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Research Materials